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皮肤胃电图的可重复性如何?一项深入的循证研究。

How reproducible is cutaneous electrogastrography? An in-depth evidence-based study.

作者信息

Jonderko K, Kasicka-Jonderko A, Krusiec-Swidergoł B, Dzielicki M, Strój L, Doliński M, Doliński K, Błońska-Fajfrowska B

机构信息

Department of Basic Biomedical Science, School of Pharmacy, Medical University of Silesia, Sosnowiec, Poland.

出版信息

Neurogastroenterol Motil. 2005 Dec;17(6):800-9. doi: 10.1111/j.1365-2982.2005.00707.x.

DOI:10.1111/j.1365-2982.2005.00707.x
PMID:16336495
Abstract

AIM

To check on reproducibility of parameters of the cutaneous electrogastrogram registered at a close or a distant time span.

METHODS

Twenty-two volunteers recruited by an advertisement (11 females and 11 males, median age 25 years, range: 18-35) underwent three surface electrogastrography examinations of which two were taken on consecutive days and the third one was accomplished at least 2 weeks before or after the two other sessions. The examination involved a 30-min fasted recording, followed by a 90-min postprandial registration after intake of a 394-kcal mixed solid-liquid test meal.

RESULTS

Parameters of the electrogastrogram pertaining to the frequency of the gastric slow waves exhibited good to moderate reproducibility, whereas fair reproducibility characterized parameters expected to describe the power of gastric slow waves. With the exception of the difference fed minus fasted power (DeltaDP), in no instance was the medium term reproducibility any worse than the short term one. Categorical data analysis revealed that the relative time share of normogastria postprandially exhibited a better reproducibility than in the fasted period. The Cohen's kappa-value of 0.459 for the DeltaDP for the medium term reproducibility placed this parameter within the range of moderate agreement between repeat examinations. Of the two two-parameter combinations considered, the alliance of the fasted and fed normogastria performed worse than any of those parameters considered alone, whereas a combination of the DeltaDP with the fed-state normogastria revealed a kappa-value amounting to 0.510 for the medium term reproducibility.

CONCLUSIONS

The feasibility of some electrogastrographic parameters to convey clinically useful information may be hampered by their fair reproducibility. Recoding of parameters of the cutaneous electrogastrogram from primary continuous to secondary categorical may help achieve a better agreement between repeat examinations.

摘要

目的

检查在相近或相隔较长时间记录的皮肤胃电图参数的可重复性。

方法

通过广告招募的22名志愿者(11名女性和11名男性,中位年龄25岁,范围:18 - 35岁)接受了三次体表胃电图检查,其中两次检查在连续两天进行,第三次检查在另外两次检查之前或之后至少2周完成。检查包括30分钟的空腹记录,随后在摄入394千卡的混合固体 - 液体试验餐后进行90分钟的餐后记录。

结果

与胃慢波频率相关的胃电图参数显示出良好至中等的可重复性,而预期用于描述胃慢波功率的参数具有中等可重复性。除了进食后减去空腹功率差(DeltaDP)外,中期可重复性在任何情况下都不比短期可重复性差。分类数据分析显示,餐后正常胃电活动的相对时间占比显示出比空腹期更好的可重复性。中期可重复性的DeltaDP的Cohen's kappa值为0.459,表明该参数在重复检查之间的一致性处于中等范围。在所考虑的两个双参数组合中,空腹和餐后正常胃电活动的联合表现比单独考虑的任何一个参数都差,而DeltaDP与餐后状态正常胃电活动的组合在中期可重复性方面的kappa值为0.510。

结论

一些胃电图参数传递临床有用信息的可行性可能因其中等可重复性而受到阻碍。将皮肤胃电图参数从原始连续记录转换为二级分类记录可能有助于在重复检查之间达成更好的一致性。

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