Eargle John, Wright Dan, Luthey-Schulten Zaida
Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, 607 South Mathews Avenue, Urbana, IL 61801, USA.
Bioinformatics. 2006 Feb 15;22(4):504-6. doi: 10.1093/bioinformatics/bti825. Epub 2005 Dec 8.
Multiple Alignment is a new interface for performing and analyzing multiple protein structure alignments. It enables viewing levels of sequence and structure similarity on the aligned structures and performing a variety of evolutionary and bioinformatic tasks, including the construction of structure-based phylogenetic trees and minimal basis sets of structures that best represent the topology of the phylogenetic tree. It is implemented as a plugin for VMD (Visual Molecular Dynamics), which is distributed by the NIH Resource for Macromolecular Modeling and Bioinformatics at the University of Illinois.
多重比对是用于执行和分析多个蛋白质结构比对的新界面。它能够查看比对结构上的序列和结构相似性水平,并执行各种进化和生物信息学任务,包括构建基于结构的系统发育树以及最能代表系统发育树拓扑结构的最小结构基集。它作为VMD(可视化分子动力学)的插件实现,VMD由伊利诺伊大学的美国国立卫生研究院大分子建模和生物信息学资源中心分发。