Amaya Enrique
The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, CB2 1QN, United Kingdom.
Genome Res. 2005 Dec;15(12):1683-91. doi: 10.1101/gr.3801805.
Xenopus genomics, or Xenomics for short, is coming of age. Indeed, biological insight into processes such as growth factor signaling and patterning of the early embryo is now being gained by combining the value of Xenopus as a model organism for cell and developmental biology with genomic approaches. In this review I address these recent advances and explore future possibilities gained from combining this powerful experimental system with genomic approaches, as well as how our quest to understand basic biological principles will be greatly facilitated though the marriage of Xenopus and genomics.
非洲爪蟾基因组学，简称爪蟾基因组学，正在走向成熟。事实上，通过将非洲爪蟾作为细胞和发育生物学模型生物的价值与基因组方法相结合，现在我们对生长因子信号传导和早期胚胎模式形成等过程有了生物学上的深入了解。在这篇综述中，我将阐述这些最新进展，并探讨将这个强大的实验系统与基因组方法相结合所带来的未来可能性，以及通过非洲爪蟾与基因组学的结合，我们对基本生物学原理的探索将如何得到极大的促进。
