Tai T Y, Chuang L M, Wu H P, Chen C J
Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Republic of China.
Int J Epidemiol. 1992 Jun;21(3):511-7. doi: 10.1093/ije/21.3.511.
Both cross-sectional and longitudinal studies on the association of body build with non-insulin-dependent diabetes mellitus (NIDDM) and hypertension were conducted in Taiwan during the period 1986-1990. The cross-sectional study, was carried out in 1986 in Ta-An District of Taipei City and five rural areas evenly distributed in Taiwan Province. A total of 11,478 randomly selected subjects aged 40 years or over were surveyed. World Health Organization designations of diabetes and hypertension were followed. The longitudinal observation was made in 1990 for the cohort living in Taipei City who had neither diabetes nor hypertension in 1986. Of 2822 subjects, 1873 individuals participated in the follow-up study and 52 had died, giving a response rate of 67.6%. In comparison with Caucasian or Polynesian populations, Chinese adults have a much lower prevalence of obesity (body mass index [BMI] greater than 30 kg/m2). Univariate and multivariate analyses revealed both diabetes and hypertension increased as body build became heavier. The age-adjusted prevalence ratio and relative risk for the fourth quartile of BMI compared to the first quartile were 2.72 and 2.87, respectively, for diabetes as well as 2.96 and 2.24, respectively, for hypertension. Multiple logistic regression analyses revealed a slightly higher increase in prevalence of hypertension than that of diabetes for every 1 kg/m2 increase in BMI (1.16-fold and 1.12-fold, respectively), while a similar increase in BMI resulted in a slightly higher relative risk of diabetes than that of hypertension (1.14-fold and 1.11-fold, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
1986年至1990年期间,台湾开展了关于体型与非胰岛素依赖型糖尿病(NIDDM)及高血压关联的横断面研究和纵向研究。横断面研究于1986年在台北市大安地区及台湾省均匀分布的五个农村地区进行。共对11478名随机选取的40岁及以上受试者进行了调查。遵循世界卫生组织对糖尿病和高血压的认定标准。纵向观察是在1990年针对1986年时既无糖尿病也无高血压的台北市队列人群进行的。在2822名受试者中,1873人参与了随访研究,52人死亡,应答率为67.6%。与白种人或波利尼西亚人群相比,中国成年人肥胖(体重指数[BMI]大于30kg/m²)的患病率要低得多。单因素和多因素分析均显示,随着体型变重,糖尿病和高血压的患病率均上升。与第一四分位数相比,BMI第四四分位数的糖尿病年龄调整患病率比和相对风险分别为2.72和2.87,高血压分别为2.96和2.24。多项逻辑回归分析显示,BMI每增加1kg/m²,高血压患病率的增幅略高于糖尿病(分别为1.16倍和1.12倍),而BMI的类似增幅导致糖尿病的相对风险略高于高血压(分别为1.14倍和1.11倍)。(摘要截短于250字)