Mandal Debayan, Panda Nilendu, Kumar Shrabanti, Banerjee Sukdeb, Mandal Nirup B, Sahu Niranjan P
Indian Institute of Chemical Biology, Department of Steroids and Terpenoids Chemistry, 4 Raja S C Mullick Road, Jadavpur, Kolkata 700 032, India.
Phytochemistry. 2006 Jan;67(2):183-90. doi: 10.1016/j.phytochem.2005.10.028. Epub 2005 Dec 15.
Bioguided-fractionation of the methanol extract of the leaves of Careya arborea led to isolation of a triterpenoid saponin, designated arborenin, and characterized as 3-O-beta-D-glucopyranosyl(1-->2)-beta-D-glucopyranosyl-2 alpha,3beta-dihydroxy-taraxast-20-en-28-oic acid (1), together with desacylescin III (2). The structures were determined on the basis of extensive 2D NMR spectroscopic analysis. The saponin showed in vitro antileishmanial activity against Leishmania donovani (strain AG 83).
对阿比西尼亚木（Careya arborea）叶甲醇提取物进行生物导向分级分离，得到一种三萜皂苷，命名为阿比西尼亚素（arborenin），其结构鉴定为3-O-β-D-吡喃葡萄糖基（1→2）-β-D-吡喃葡萄糖基-2α，3β-二羟基蒲公英赛-20-烯-28-酸（1），同时还得到了去酰基辛可宁三糖苷（desacylescin III，2）。通过广泛的二维核磁共振光谱分析确定了其结构。该皂苷对杜氏利什曼原虫（菌株AG 83）显示出体外抗利什曼原虫活性。
