狭叶番泻种子中生物活性三萜皂苷的抗真菌活性
Antifungal activity of bioactive triterpenoid saponin from the seeds of Cassia angustifolia.
作者信息
Khan Noor Afshan, Srivastava Ashutosh
机构信息
Department of Postgraduate and Research in Chemistry, Rani Durgawati University, Jabalpur, India.
出版信息
Nat Prod Res. 2009;23(12):1128-33. doi: 10.1080/14786410802625279.
A novel oleanen type triterpenoid glycoside has been isolated from butanolic seed extracts of Cassia angustifolia. Its structure was elucidated as 3-O-{beta-D-glucuronopyranosyl-(1 --> 4)-[beta-D-galactopyranosyl-(1 --> 2)]-beta-D-xylopyranosyl-(1 --> 3)-beta-D-glucopyranosyl}-2, 16alpha-dihydroxy-4, 20-hydroxy methyl olean-12-ene-28-oic acid on the basis of spectral evidence (i.e. FTIR, (1)H NMR, (13)C NMR and FAB-MS data). The isolated saponin was tested for its antifungal activity, where the maximum inhibition was found in Colletotrichium dematium.
从窄叶决明的丁醇种子提取物中分离出一种新型齐墩果烷型三萜糖苷。基于光谱证据（即傅里叶变换红外光谱、¹H核磁共振、¹³C核磁共振和快原子轰击质谱数据），其结构被鉴定为3-O-{β-D-葡萄糖醛酸吡喃糖基-(1→4)-[β-D-半乳糖吡喃糖基-(1→2)]-β-D-木糖吡喃糖基-(1→3)-β-D-葡萄糖吡喃糖基}-2,16α-二羟基-4,20-羟甲基齐墩果-12-烯-28-酸。对分离得到的皂苷进行了抗真菌活性测试，发现其对炭疽菌的抑制作用最强。
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