Tochigi Research Laboratories of Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321-34, and Wakayama Research Laboratories of Kao Corporation, 1334 Minato, Wakayama 640, Japan.
Appl Environ Microbiol. 1993 May;59(5):1336-41. doi: 10.1128/aem.59.5.1336-1341.1993.
A bacterial strain, designated KSM-7358, that can use alpha-cedrene for growth was isolated. The strain was identified as a member of the genus Rhodococcus and catalyzed the novel allylic oxidation of alpha-cedrene regiospecifically to produce (R)-10-hydroxycedrene (sec-cedrenol) with a very high yield. alpha-Curcumene was also produced as a possible metabolite of sec-cedrenol. A possible pathway for the microbial conversion of alpha-cedrene to sec-cedrenol and alpha-curcumene is proposed.
一株能以α-芹子烯为生长基质的细菌菌株 KSM-7358 被分离出来。该菌株被鉴定为红球菌属的一个成员，能对 α-芹子烯进行新型的烯丙位氧化，以高收率立体专一性地生成 (R)-10-羟基-α-芹子烯（β-芹子醇）。顺-金合欢烯可能是 β-芹子醇的一种代谢产物。提出了微生物将 α-芹子烯转化为 β-芹子醇和顺-金合欢烯的可能途径。
