Aires C P, Tabchoury C P M, Del Bel Cury A A, Koo H, Cury J A
Faculty of Dentistry of Piracicaba, UNICAMP, Piracicaba, Brazil.
Caries Res. 2006;40(1):28-32. doi: 10.1159/000088902.
The relationship between sucrose concentration and cariogenic potential was studied in situ. Adult volunteers wore intraoral palatal appliances containing human dental enamel blocks, which were extraorally submitted 8 times a day for 14 days, to the treatments: deionized distilled water and sucrose solutions from 1 to 40%. The biofilm formed was analyzed with respect to acidogenicity and biochemical composition; enamel demineralization was evaluated by microhardness. The results showed that 1% sucrose is less cariogenic than 5% or higher concentrations, although sucrose solution at 40% was still able to increase the concentration of insoluble polysaccharide in the biofilm formed. The findings suggest that the threshold of sucrose solution concentration for the formation of a cariogenic biofilm is 5%, which provided the same cariogenic potential as that observed for 10 and 20% sucrose solution.
对蔗糖浓度与致龋潜力之间的关系进行了原位研究。成年志愿者佩戴含有人类牙釉质块的口内腭部装置，这些装置每天8次被带到口腔外，持续14天，接受以下处理：去离子蒸馏水和1%至40%的蔗糖溶液。对形成的生物膜进行了产酸性和生化成分分析；通过显微硬度评估牙釉质脱矿情况。结果表明，1%的蔗糖致龋性低于5%或更高浓度，尽管40%的蔗糖溶液仍能增加所形成生物膜中不溶性多糖的浓度。研究结果表明，形成致龋生物膜的蔗糖溶液浓度阈值为5%，其致龋潜力与10%和20%的蔗糖溶液相同。
