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颅内海绵状血管瘤。

Intracranial cavernous angioma.

作者信息

Ferrante L, Palma L, d'Addetta R, Mastronardi L, Acqui M, Fortuna A

机构信息

Department of Neurological Sciences, University of Rome La Sapienza, Italy.

出版信息

Neurosurg Rev. 1992;15(2):125-33. doi: 10.1007/BF00313508.

Abstract

We report 14 cases of intracranial cavernous angioma, analyzing the clinical features, with special reference to the risk of bleeding, radiological images and treatment in these and in 153 published cases, 167 in all. Cerebral hemorrhage occurred in 44%: typical (intraparenchymal or subarachnoid) in 24.6%, and masked by epilepsy, headache or neurological deficits in 19.2%. In patients with the typical hemorrhagic pattern posthemorrhagic mortality was 12.2%. Of the patients who had a hemorrhage 42.5% were left with more or less disabling neurological deficits, and 16.4% had a rebleed. In discussing treatment we consider four groups of intracranial cavernous angioma: A) symptomatic in a zone of low surgical risk; B) asymptomatic with low surgical risk; C) symptomatic with high surgical risk; D) asymptomatic with high surgical risk. The treatment is surgical, except in the high risk asymptomatic variety, best followed initially with sequential CT scan and MRI and then considered for surgery if the lesion becomes symptomatic, increases in size or presents neuroradiological signs of bleeding.

摘要

我们报告了14例颅内海绵状血管瘤病例,分析了其临床特征,特别提及了这些病例以及153例已发表病例(共167例)中的出血风险、放射影像及治疗情况。脑出血发生率为44%:典型脑出血(脑实质内或蛛网膜下腔出血)占24.6%,因癫痫、头痛或神经功能缺损而表现隐匿的占19.2%。典型出血模式患者的出血后死亡率为12.2%。出血患者中,42.5%或多或少遗留有致残性神经功能缺损,16.4%发生再出血。在讨论治疗方法时,我们将颅内海绵状血管瘤分为四组:A)手术风险低的有症状型;B)手术风险低的无症状型;C)手术风险高的有症状型;D)手术风险高的无症状型。除高风险无症状型外,治疗方法为手术治疗,最初最好先进行连续CT扫描和MRI检查,若病变出现症状、增大或出现神经放射学出血征象,则考虑手术治疗。

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