Fortuna A, Ferrante L, Mastronardi L, Acqui M, d'Addetta R
Dipartimento di Scienze Neurologiche, Università di Roma, Italy.
Childs Nerv Syst. 1989 Aug;5(4):201-7. doi: 10.1007/BF00271020.
Cerebral cavernous angioma is a rare vascular malformation at any age and is very rare in childhood. In the literature available to us, we have been able to trace only 50 cases, to which we have added the 6 cases from our own series. The incidence in pediatric group is higher at 0-2 years (26.8%) and at 13-16 years (35.7%). The clinical onset shows epilepsy in 45.4% of cases, hemorrhagic syndrome in 27.3%, intracranial hypertension in 16.4%, and focal neurological deficits in 10.9%. Furthermore, we discuss the neuroradiological features (CT, angiography, and MRI) and the therapy of pediatric cavernous angioma.
脑海绵状血管瘤在任何年龄都是一种罕见的血管畸形，在儿童期极为罕见。在我们所能获取的文献中，我们仅能追溯到50例，我们自己的系列病例中又增加了6例。小儿组发病率在0 - 2岁时较高（26.8%），在13 - 16岁时也较高（35.7%）。临床起病表现为癫痫的占45.4%，出血综合征占27.3%，颅内高压占16.4%，局灶性神经功能缺损占10.9%。此外，我们还讨论了小儿脑海绵状血管瘤的神经放射学特征（CT、血管造影和MRI）及治疗方法。
