关于从德国两个湖泊分离出的产柱孢藻毒素的水华束丝藻（蓝细菌）的首次报告。

First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes.

作者信息

Preussel Karina, Stüken Anke, Wiedner Claudia, Chorus Ingrid, Fastner Jutta

机构信息

Federal Environmental Agency, FG II 3.3, Corrensplatz 1, 14195 Berlin, Germany.

出版信息

Toxicon. 2006 Feb;47(2):156-62. doi: 10.1016/j.toxicon.2005.10.013. Epub 2005 Dec 13.

DOI:10.1016/j.toxicon.2005.10.013

PMID:16356522

Abstract

Three single-filament isolates of Aphanizomenon flos-aquae from two German lakes were found to produce remarkable amounts of the cyanobacterial hepatotoxin cylindrospermopsin (CYN). CYN-synthesis of the strains were evidenced both by LC-MS/MS analysis and detection of PCR products of gene fragments which are implicated in the biosynthesis of the toxin. The strains contain CYN in the range of 2.3-6.6 mg g(-1) of cellular dry weight. To our knowledge this is the first report of CYN in A. flos-aquae.

摘要

从德国两个湖泊中分离出的三株丝状水华束丝藻被发现能产生大量的蓝藻肝毒素柱孢藻毒素（CYN）。通过液相色谱-串联质谱（LC-MS/MS）分析以及检测与该毒素生物合成相关的基因片段的PCR产物，证实了这些菌株能够合成CYN。这些菌株细胞干重中CYN的含量在2.3 - 6.6毫克/克之间。据我们所知，这是关于水华束丝藻中存在CYN的首次报道。