韩国丁基羟基茴香醚（BHA）、丁基羟基甲苯（BHT）和特丁基对苯二酚（TBHQ）抗氧化剂的每日估计摄入量。

Estimated daily intakes of butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and tert-butyl hydroquinone (TBHQ) antioxidants in Korea.

作者信息

Suh H-J, Chung M-S, Cho Y-H, Kim J-W, Kim D-H, Han K-W, Kim C-J

机构信息

Korea Health Industry Development Institute, 57-1 Noryangjin-Dong, Seoul 156-800, Korea.

出版信息

Food Addit Contam. 2005 Dec;22(12):1176-88. doi: 10.1080/02652030500195288.

DOI:10.1080/02652030500195288

PMID:16356880

Abstract

The study was conducted to establish the estimated daily intake (EDI) of antioxidants such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and tert-butyl hydroquinone (TBHQ) in Korea. The EDIs were obtained from two sources. One of the estimations was based on the analytical determination of BHA, BHT and TBHQ in 12 food categories (ten food categories for TBHQ) and on individual dietary intake data obtained from the National Health and Nutrition Survey in 1998 (n=11 525, age > 1 year). The other EDIs of BHA, BHT and TBHQ were based on the maximum permitted levels specified in national food standards in Korea and on individual dietary intake data obtained from the National Health and Nutrition Survey in 1998 (n=11 525, age > 1 year). To establish the EDIs based on the analytical determination and on individual dietary intake data, 133 food samples in 12 food categories were selected from the foods considered to be representative sources of BHA, BHT and TBHQ in the Korean diet. Selected samples were analysed by GC with FID. BHA was not detected in any of the samples analysed. BHT and TBHQ were detected in the samples, but the levels were significantly lower than their maximum limits. The EDIs1 of BHT, and TBHQ for average consumers were 0.0156(-3), and 0.0012(-3) mg kg(-1) body weight bw day(-1) and as a proportion of the ADI were 0.0052 and 0.0002%, respectively. For 95th percentile consumers, the EDIs of BHT and TBHQ were 0.0080 and 0.0006 mg kg(-1) bw day(-1), and as a proportion of the ADI were 2.67 and 0.09%, respectively. EDIs for BHA, BHT and TBHQ based on the maximum permitted levels and on individual dietary intake data were 0.04, 0.04 and 0.04 mg kg(-1) bw day(-1), respectively. The EDIs of BHA, BHT and TBHQ for average consumers ranged from 6.00 to 14.42% of the ADI of each antioxidant. According to these results, the EDIs of BHA, BHT and TBHQ in Korea were significantly lower than ADI of these antioxidants established by the JECFA.

摘要

本研究旨在确定韩国人群抗氧化剂如丁基羟基茴香醚（BHA）、二丁基羟基甲苯（BHT）和叔丁基对苯二酚（TBHQ）的估计每日摄入量（EDI）。EDI来自两个来源。其中一种估计是基于对12类食品（TBHQ为10类食品）中BHA、BHT和TBHQ的分析测定，以及从1998年韩国国民健康与营养调查中获得的个人饮食摄入数据（n = 11525，年龄>1岁）。BHA、BHT和TBHQ的其他EDI是基于韩国国家食品标准规定的最大允许水平，以及从1998年韩国国民健康与营养调查中获得的个人饮食摄入数据（n = 11525，年龄>1岁）。为了基于分析测定和个人饮食摄入数据确定EDI，从韩国饮食中被认为是BHA、BHT和TBHQ代表性来源的食品中，选择了12类食品中的133个食品样本。对所选样本采用带氢火焰离子化检测器（FID）的气相色谱法（GC）进行分析。在所分析的任何样本中均未检测到BHA。在样本中检测到了BHT和TBHQ，但其水平显著低于其最大限量。普通消费者的BHT和TBHQ的EDI分别为0.0156（-3）和0.0012（-3）mg·kg-1体重·bw·天-1，占每日允许摄入量（ADI）的比例分别为0.0052%和0.0002%。对于第95百分位数的消费者，BHT和TBHQ的EDI分别为0.0080和mg·kg-1·bw·天-1，占ADI的比例分别为2.67%和0.09%。基于最大允许水平和个人饮食摄入数据的BHA、BHT和TBHQ的EDI分别为0.04、0.04和0.04mg·kg-1·bw·天-1。普通消费者的BHA、BHT和TBHQ的EDI占各抗氧化剂ADI的6.00%至14.42%。根据这些结果，韩国BHA、BHT和TBHQ的EDI显著低于食品添加剂联合专家委员会（JECFA）确定的这些抗氧化剂的ADI。