André Malin, Eriksson Margareta, Mölstad Sigvard, Stålsbylundborg Cecilia, Jacobsson Anders, Odenholt Inga
Centre for Clinical Research, Falun, Sweden.
Scand J Infect Dis. 2005;37(11-12):863-9. doi: 10.1080/00365540500335207.
A diagnosis-prescribing study was performed in 5 Swedish counties during 1 week in November in 2000 and repeated in 2002. The aim of the present study was to analyse data for children 0-15y of age who consulted a general practitioner with symptoms of an infection. During the 2 weeks studied, 4049 children were consulted. Respiratory tract infections (RTI) were the predominant diagnoses, above all among the youngest children, while the proportion of urinary tract infections and skin infections increased with increasing age. Between the y 2000 and 2002, the proportion of children allocated the diagnosis streptococcal tonsillitis and pneumonia decreased (p<0.01 and p<0.001, respectively) while the proportion of common cold increased (p<0.001). Antibiotic prescribing decreased from 55% to 48% (p<0.001) for respiratory infections between the years studied. The only significant changes in type of antibiotics prescribed were the increase of isoxazolylpenicillins (p<0.001) used for skin infection and the decrease of macrolides (p=0.001). A diagnostic test was used in more than half of the consultations. Of children allocated a RTI diagnosis, 36% were prescribed antibiotics when a C-reactive protein test was performed compared to 58% in those not tested. Further studies are needed in general practice to determine the optimal use of near-patient tests in children with RTI.
2000年11月的1周内在瑞典5个郡开展了一项诊断-处方研究,并于2002年重复进行。本研究的目的是分析0至15岁因感染症状咨询全科医生的儿童的数据。在研究的2周内,有4049名儿童前来咨询。呼吸道感染(RTI)是主要诊断,在最小的儿童中尤为突出,而尿路感染和皮肤感染的比例随年龄增长而增加。在2000年至2002年期间,被诊断为链球菌性扁桃体炎和肺炎的儿童比例下降(分别为p<0.01和p<0.001),而普通感冒的比例增加(p<0.001)。在所研究的年份之间,呼吸道感染的抗生素处方率从55%降至48%(p<0.001)。所开抗生素类型的唯一显著变化是用于皮肤感染的异恶唑青霉素增加(p<0.001),大环内酯类减少(p=0.001)。超过一半的咨询使用了诊断测试。在被诊断为RTI的儿童中,进行C反应蛋白测试的儿童中有36%被开了抗生素,而未进行测试的儿童中这一比例为58%。在全科医疗中需要进一步研究以确定在患有RTI的儿童中即时检验的最佳使用方法。