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本文引用的文献

1
Diagnosis-prescribing surveys in 2000, 2002 and 2005 in Swedish general practice: consultations, diagnosis, diagnostics and treatment choices.2000年、2002年和2005年瑞典全科医疗中的诊断-处方调查:会诊、诊断、诊断方法及治疗选择
Scand J Infect Dis. 2008;40(8):648-54. doi: 10.1080/00365540801932439.
2
Sustained reduction of antibiotic use and low bacterial resistance: 10-year follow-up of the Swedish Strama programme.抗生素使用的持续减少与低细菌耐药性:瑞典Strama项目的10年随访
Lancet Infect Dis. 2008 Feb;8(2):125-32. doi: 10.1016/S1473-3099(08)70017-3.
3
European Surveillance of Antimicrobial Consumption (ESAC): quality indicators for outpatient antibiotic use in Europe.欧洲抗菌药物消费监测(ESAC):欧洲门诊抗生素使用的质量指标
Qual Saf Health Care. 2007 Dec;16(6):440-5. doi: 10.1136/qshc.2006.021121.
4
Evaluation of phenoxymethylpenicillin treatment of acute otitis media in children aged 2-16.对2至16岁儿童急性中耳炎采用苯氧甲基青霉素治疗的评估。
Scand J Prim Health Care. 2007 Sep;25(3):166-71. doi: 10.1080/02813430701267405.
5
Age-related changes in consultations and antibiotic prescribing for acute respiratory infections, 1995-2000. Data from the UK General Practice Research Database.1995 - 2000年急性呼吸道感染门诊及抗生素处方的年龄相关变化。来自英国全科医疗研究数据库的数据。
J Clin Pharm Ther. 2006 Oct;31(5):461-7. doi: 10.1111/j.1365-2710.2006.00765.x.
6
Management of upper respiratory tract infections in Dutch general practice; antibiotic prescribing rates and incidences in 1987 and 2001.荷兰全科医疗中对上呼吸道感染的管理;1987年和2001年的抗生素处方率及发病率
Fam Pract. 2006 Apr;23(2):175-9. doi: 10.1093/fampra/cmi122. Epub 2006 Feb 3.
7
The management of infections in children in general practice in Sweden: a repeated 1-week diagnosis-prescribing study in 5 counties in 2000 and 2002.瑞典全科医疗中儿童感染的管理:2000年和2002年在5个县进行的一项为期1周的重复诊断-处方研究。
Scand J Infect Dis. 2005;37(11-12):863-9. doi: 10.1080/00365540500335207.
8
Antibiotics for the common cold and acute purulent rhinitis.用于普通感冒和急性化脓性鼻炎的抗生素。
Cochrane Database Syst Rev. 2005 Jul 20(3):CD000247. doi: 10.1002/14651858.CD000247.pub2.
9
Preferred antibiotics, dosages and length of treatments in general practice--a comparison between ten European countries.全科医疗中首选抗生素、剂量及治疗时长——十个欧洲国家之间的比较
Eur J Gen Pract. 2004 Dec;10(4):166-8. doi: 10.3109/13814780409044306.
10
Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database.为何基层医疗中呼吸道疾病的抗生素处方量有所下降?一项使用全科医疗研究数据库的纵向研究。
J Public Health (Oxf). 2004 Sep;26(3):268-74. doi: 10.1093/pubmed/fdh160.

1999年至2005年期间瑞典南部卡尔马县初级医疗保健中呼吸道感染的会诊次数和抗生素处方数量趋势。

Trends in number of consultations and antibiotic prescriptions for respiratory tract infections between 1999 and 2005 in primary healthcare in Kalmar County, Southern Sweden.

作者信息

Neumark Thomas, Brudin Lars, Engstrom Sven, Molstad Sigvard

机构信息

Lindsdals Primary Health Centre, Förlösavägen 4, Kalmar, Sweden.

出版信息

Scand J Prim Health Care. 2009;27(1):18-24. doi: 10.1080/02813430802610784.

DOI:10.1080/02813430802610784
PMID:19085427
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3410472/
Abstract

UNLABELLED

BACKGROUND. Respiratory tract infections (RTIs) comprise the most common indication for consulting a general practitioner and obtaining an antibiotic prescription.

OBJECTIVE

To study changes in the number of visits, diagnoses, and antibiotic prescriptions for RTI in primary healthcare during the period 1999-2005.

DESIGN

A retrospective, descriptive, population-based study of electronic patient records. Setting. County of Kalmar in southeastern Sweden.

PATIENTS

Patients visiting primary healthcare units in Kalmar County for an RTI between 1 July 1999 and 31 December 2005.

MAIN OUTCOME MEASURES

RTI diagnoses, antibiotic prescriptions, age groups.

RESULTS

A total of 240 447 visits for RTI made between 1999 and 2005 were analysed. The yearly consultation rates for the diagnoses acute tonsillitis and AOM decreased by 12% and 10%, respectively (p = 0.001). Of all patients consulting for an RTI diagnosis, 45% received antibiotics. Of all prescribed antibiotics, 60% were for phenoxymethylpenicillin (PcV) and 18% doxycycline. Amoxicillin or amoxicillin + clavulanic acid was prescribed to a lesser extent. The proportion of patients obtaining an antibiotic prescription was almost constant over time (44-46%). The prescriptions of doxycycline showed increasing values (NS). The prescriptions of remaining antibiotics decreased significantly especially for patients up to middle age.

CONCLUSION

This large population study, comprising more than six years of observations, showed the number of primary healthcare patients receiving an RTI diagnosis decreased during the period 1999-2005, but the proportion of patients receiving an antibiotic prescription remained the same. The large seasonal variations indicate a need for further interventions to decrease antibiotic use for RTIs.

摘要

未加标注

背景。呼吸道感染(RTIs)是咨询全科医生并获取抗生素处方最常见的原因。

目的

研究1999 - 2005年期间基层医疗中呼吸道感染就诊次数、诊断及抗生素处方的变化。

设计

基于电子病历的回顾性、描述性、人群研究。地点。瑞典东南部卡尔马县。

患者

1999年7月1日至2005年12月31日期间因呼吸道感染到卡尔马县基层医疗单位就诊的患者。

主要观察指标

呼吸道感染诊断、抗生素处方、年龄组。

结果

分析了1999年至2005年期间共240447次呼吸道感染就诊情况。急性扁桃体炎和急性中耳炎诊断的年就诊率分别下降了12%和10%(p = 0.001)。在所有因呼吸道感染诊断而就诊的患者中,45%接受了抗生素治疗。在所有开具的抗生素中,60%为青霉素V(PcV),18%为强力霉素。阿莫西林或阿莫西林+克拉维酸的处方比例较低。随时间推移,获得抗生素处方的患者比例几乎保持不变(44 - 46%)。强力霉素的处方量呈上升趋势(无统计学意义)。其余抗生素的处方量显著下降,尤其是中年及以下患者。

结论

这项包含六年多观察的大型人群研究表明,1999 - 2005年期间接受呼吸道感染诊断的基层医疗患者数量有所下降,但接受抗生素处方的患者比例保持不变。较大的季节性差异表明需要进一步干预以减少呼吸道感染的抗生素使用。