Tarhan Fatih, Orçun Asuman, Küçükercan Inci, Camursoy Nazan, Kuyumcuoğlu Uğur
Urology Clinic, Kartal Training and Research Hospital, Istanbul, Turkey.
Urology. 2005 Dec;66(6):1234-8. doi: 10.1016/j.urology.2005.06.077.
To evaluate the effects of prostatic massage on the serum complexed PSA (cPSA) concentration in various prostatic diseases.
A total of 51 men who presented to our outpatient clinic for the first time with symptoms of lower urinary outflow obstruction were included in this study. Blood samples were obtained from each patient before and 30 minutes after prostatic massage. Total PSA (tPSA), free PSA (fPSA), and cPSA levels were measured using a chemiluminescent enzyme immunoassay.
After prostatic massage, the tPSA and fPSA levels and fPSA/tPSA ratio increased significantly (P < 0.0001), and the increase in cPSA was minimal but statistically significant (P = 0.047). In patients with prostate cancer, no significant increase occurred in the mean forms of PSA (tPSA, cPSA, and fPSA/tPSA ratio), except for fPSA, after prostatic massage. We observed a greater increase in all PSA forms in the chronic prostatitis group.
In this study, prostatic massage increased serum cPSA concentration, but to a lesser extent than tPSA and fPSA.
评估前列腺按摩对各种前列腺疾病患者血清复合前列腺特异性抗原（cPSA）浓度的影响。
本研究纳入了51例首次因下尿路梗阻症状前来我院门诊就诊的男性患者。在前列腺按摩前及按摩后30分钟采集每位患者的血样。采用化学发光酶免疫分析法测定总前列腺特异性抗原（tPSA）、游离前列腺特异性抗原（fPSA）和cPSA水平。
前列腺按摩后，tPSA和fPSA水平以及fPSA/tPSA比值显著升高（P < 0.0001），cPSA的升高幅度最小，但具有统计学意义（P = 0.047）。在前列腺癌患者中，前列腺按摩后除fPSA外，PSA的平均形式（tPSA、cPSA和fPSA/tPSA比值）无显著升高。我们观察到慢性前列腺炎组中所有PSA形式的升高幅度更大。
在本研究中，前列腺按摩可提高血清cPSA浓度，但幅度小于tPSA和fPSA。
