Chuang H C, Kawano S, Arai M, Tsukada T, Kita M, Negi A, Honda Y
Department of Ophthalmology, Faculty of Medicine, Kyoto University, Japan.
Acta Ophthalmol (Copenh). 1992 Jun;70(3):303-7. doi: 10.1111/j.1755-3768.1992.tb08568.x.
We observed the influence of panretinal photocoagulation on the ERG c-wave in rabbit eyes. DC-registered ERGs were recorded from rabbit eyes before and after photocoagulation, and compared with those of the fellow eyes. The rabbits were subdivided into 3 groups according to application numbers: 500, 1000, and 1500 spots. The ERG c-waves were found to have totally disappeared in all rabbits 3 days after panretinal photocoagulation, then reappeared with various intervals. In the 500 spot group, the c-wave reappeared after one week, and almost reached control levels in one and a half months. In the 1000 spot group, a 10 day delay was noted, and 90% of control levels were regained after 6 months. In the 1500 spot group, the c-wave didn't reappear until 2 weeks later, and regained 70% (of the control level) after 6 months. The recovery rates were related to the number of laser applications. These results indicate that the ultimate degree of recovery in c-wave amplitude and the time required for the reestablishment of retinal pigment epithelium function both depend on the size of the coagulated area.
我们观察了全视网膜光凝对兔眼视网膜电图c波的影响。在光凝前后记录兔眼的直流记录视网膜电图，并与对侧眼进行比较。根据光凝光斑数量将兔子分为3组：500个、1000个和1500个光斑。发现全视网膜光凝后3天，所有兔子的视网膜电图c波完全消失，然后在不同间隔后重新出现。在500光斑组中，c波在1周后重新出现，在1个半月时几乎达到对照水平。在1000光斑组中，观察到延迟10天，6个月后恢复到对照水平的90%。在1500光斑组中，c波直到2周后才重新出现，6个月后恢复到对照水平的70%。恢复率与激光照射次数有关。这些结果表明，c波振幅的最终恢复程度和视网膜色素上皮功能重建所需的时间均取决于凝固区域的大小。
