Imai M, Iijima H
Department of Ophthalmology, Yamanashi Medical College, Japan.
Jpn J Ophthalmol. 1995;39(2):120-3.
The effects of panretinal photocoagulation (PRP) on photopic ERG were studied in normal pigmented rabbit eyes. Photopic ERGs were recorded before PRP and one day, one week and 4 weeks after PRP. Markedly reduced amplitude and delayed implicit time were observed one day after PRP. Four weeks after PRP, amplitude showed subtotal recovery while implicit time, showing tendency of reduction, was still significantly delayed. The delay in implicit time and the reduction in amplitude after PRP was probably due to serous retinal detachment and/or retinal edema caused by breakdown of the blood-retinal barrier. However, the findings at 4 weeks after PRP might be explained by the reduced number of photoreceptor cells; the mild decrease in the amplitude of photopic ERG might be caused by the reduced number of cones, while significantly delayed implicit time of the photopic ERG might be caused by reduced number of rods.
在正常色素沉着兔眼中研究了全视网膜光凝（PRP）对明视视网膜电图（ERG）的影响。在PRP之前以及PRP后1天、1周和4周记录明视ERG。PRP后1天观察到振幅明显降低和潜伏期延迟。PRP后4周，振幅显示部分恢复，而潜伏期虽有缩短趋势但仍明显延迟。PRP后潜伏期延迟和振幅降低可能是由于血视网膜屏障破坏导致的浆液性视网膜脱离和/或视网膜水肿。然而，PRP后4周的结果可能是由于光感受器细胞数量减少所致；明视ERG振幅的轻度降低可能是由于视锥细胞数量减少，而明视ERG潜伏期明显延迟可能是由于视杆细胞数量减少。
