DeBarry Jeremy D, Ganko Eric W, McCarthy Eugene M, McDonald John F
Mol Biol Evol. 2006 Mar;23(3):479-81. doi: 10.1093/molbev/msj076. Epub 2005 Dec 20.
Approximately 1.5% of mouse genes (Mus musculus) contain long terminal repeat retrotransposon sequences (LRS). Consistent with earlier findings in Caenorhabditis elegans, Drosophila melanogaster, and Homo sapiens, LRS are more likely to be associated with newly evolved genes. Evidence is presented that LRS are often recruited as novel exons or as spliced additions to existing exons. These novel gene configurations may be expressed initially as alternative transcripts providing an opportunity for the evolution of new gene function.
大约1.5%的小鼠基因（小家鼠）包含长末端重复逆转座子序列（LRS）。与先前在秀丽隐杆线虫、黑腹果蝇和智人中的发现一致，LRS更有可能与新进化的基因相关联。有证据表明，LRS经常被招募为新的外显子或作为现有外显子的剪接添加物。这些新的基因结构最初可能作为可变转录本表达，为新基因功能的进化提供了机会。
