Pierce T B, Margolis M, Razzuk M A
The University of North Texas Health Science Center, Ft. Worth, Texas, USA.
Proc (Bayl Univ Med Cent). 2001 Jan;14(1):8-12. doi: 10.1080/08998280.2001.11927724.
Sarcoidosis is a systemic granulomatous disease of unknown etiology. It has diverse clinical manifestations, most frequently including pulmonary disorders. It is associated with immunological abnormalities, the intricacies of which have yet to be clearly delineated. In the immunologically susceptible individual, genetic, environmental, nutritional, and socioeconomic factors may play a governing role in its development. Sarcoidosis is a diagnosis of exclusion established by clinical manifestations, radiologic findings, and histologic evidence of noncaseating epithelioid-cell granulomas in >1 organ. We will discuss parameters that are helpful in making this diagnosis.
结节病是一种病因不明的全身性肉芽肿性疾病。它有多种临床表现，最常见的包括肺部疾病。它与免疫异常有关，其复杂情况尚未完全明确。在免疫易感个体中，遗传、环境、营养和社会经济因素可能在其发病过程中起主导作用。结节病是一种排除性诊断，通过临床表现、影像学检查结果以及一个以上器官出现非干酪样上皮样细胞肉芽肿的组织学证据来确立。我们将讨论有助于做出这一诊断的参数。
