Tawde Poonam, Mohammad Salim
Physiotherapy, Sancheti institute for Orthopaedics and Rehabilitation, Pune, IND.
Medical School, Avalon University School of Medicine, Willemstad, CUW.
Cureus. 2024 Jan 31;16(1):e53272. doi: 10.7759/cureus.53272. eCollection 2024 Jan.
This study explores the complex interplay between coccidioidomycosis (valley fever) and sarcoidosis through a detailed case study of a 54-year-old male patient. The patient presented with elevated calcium levels, chronic kidney disease (CKD), and unintended weight loss. Interdisciplinary collaboration between nephrologists and pulmonologists played a crucial role in navigating the intricate medical challenges, including hypercalcemia, renal dysfunction, and pulmonary anomalies. The diagnostic journey involved extensive laboratory findings uncovering the involvement of both infectious agents and granulomatous disorders. The patient exhibited positive cocci IgG antibodies, indicating coccidioidomycosis. Further complications included glomerulonephritis, as revealed by ongoing systemic inflammation. Tailored management strategies were implemented, including corticosteroid therapy for sarcoidosis-related inflammation and antifungal interventions for coccidioidomycosis. Vigilant monitoring of renal function, hypercalcemia, and weight loss was essential for comprehensive patient care. The study underscores the significance of interdisciplinary collaboration, systematic diagnostics, and personalized patient care in managing complex medical presentations and contributes to understanding the interplay between these two conditions.
本研究通过对一名54岁男性患者的详细病例研究,探讨了球孢子菌病(谷热)和结节病之间复杂的相互作用。该患者出现血钙水平升高、慢性肾脏病(CKD)和意外体重减轻。肾病学家和肺科医生之间的跨学科合作在应对包括高钙血症、肾功能不全和肺部异常等复杂医学挑战中发挥了关键作用。诊断过程涉及广泛的实验室检查结果,揭示了感染因子和肉芽肿性疾病的参与。患者球孢子菌IgG抗体呈阳性,表明患有球孢子菌病。持续的全身炎症显示进一步的并发症包括肾小球肾炎。实施了量身定制的管理策略,包括针对结节病相关炎症的皮质类固醇治疗和针对球孢子菌病的抗真菌干预措施。对肾功能、高钙血症和体重减轻进行密切监测对全面的患者护理至关重要。该研究强调了跨学科合作、系统诊断和个性化患者护理在管理复杂医学表现中的重要性,并有助于理解这两种疾病之间的相互作用。