• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

利用转基因陆地植物生产含二十碳五烯酸和二十二碳六烯酸的油脂用于人类和水产养殖营养。

Production of eicosapentaenoic and docosahexaenoic acid-containing oils in transgenic land plants for human and aquaculture nutrition.

作者信息

Robert Stanley S

机构信息

Food Futures National Research Flagship Division of Marine and Atmospheric Research, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Hobart, Tasmania 7001, Australia.

出版信息

Mar Biotechnol (NY). 2006 Mar-Apr;8(2):103-9. doi: 10.1007/s10126-005-5142-x. Epub 2006 Jan 1.

DOI:10.1007/s10126-005-5142-x
PMID:16372159
Abstract

A large body of evidence suggests that there is a significant underconsumption of omega-3, long-chain, polyunsaturated fatty acids (LC-PUFAs) and that this is the cause of multiple chronic diseases and developmental aberrations. The scope for increasing omega-3 LC-PUFA consumption from seafood is limited because global wild fisheries are unable to increase their harvests, and aquaculture fisheries currently rely on wild fisheries as a source of LC-PUFAs. Agricultural production of oils is highly efficient and has the potential to be sustainable. The transfer of genes from marine microalgae and other microorganisms into oilseed crops has shown that the production of terrestrial omega-3 LC-PUFA oils is indeed possible. The specifications of these oils or whole seeds for use in human and Atlantic salmon (Salmo salar) aquaculture nutrition are discussed.

摘要

大量证据表明,ω-3长链多不饱和脂肪酸(LC-PUFAs)的摄入量严重不足,这是多种慢性疾病和发育异常的原因。通过海鲜增加ω-3 LC-PUFA摄入量的空间有限,因为全球野生渔业无法增加产量,而水产养殖目前依赖野生渔业作为LC-PUFAs的来源。油料作物的农业生产效率很高,并且具有可持续发展的潜力。将海洋微藻和其他微生物的基因转移到油料作物中已表明,在陆地上生产ω-3 LC-PUFA油确实是可行的。本文讨论了这些油或整粒种子用于人类和大西洋鲑鱼(Salmo salar)水产养殖营养的规格。

相似文献

1
Production of eicosapentaenoic and docosahexaenoic acid-containing oils in transgenic land plants for human and aquaculture nutrition.利用转基因陆地植物生产含二十碳五烯酸和二十二碳六烯酸的油脂用于人类和水产养殖营养。
Mar Biotechnol (NY). 2006 Mar-Apr;8(2):103-9. doi: 10.1007/s10126-005-5142-x. Epub 2006 Jan 1.
2
Microbial and genetically engineered oils as replacements for fish oil in aquaculture feeds.微生物油和基因工程油作为水产养殖饲料中鱼油的替代品。
Biotechnol Lett. 2017 Nov;39(11):1599-1609. doi: 10.1007/s10529-017-2402-6. Epub 2017 Jul 18.
3
Molecular cloning and functional characterization of fatty acyl desaturase and elongase cDNAs involved in the production of eicosapentaenoic and docosahexaenoic acids from alpha-linolenic acid in Atlantic salmon (Salmo salar).参与大西洋鲑(Salmo salar)从α-亚麻酸生成二十碳五烯酸和二十二碳六烯酸过程的脂肪酰去饱和酶和延长酶cDNA的分子克隆及功能表征
Mar Biotechnol (NY). 2004 Sep-Oct;6(5):463-74. doi: 10.1007/s10126-004-3002-8. Epub 2004 Nov 4.
4
Transgenic oilseed crops as an alternative to fish oils.转基因油料作物作为鱼油的替代品。
Prostaglandins Leukot Essent Fatty Acids. 2011 Nov;85(5):253-60. doi: 10.1016/j.plefa.2011.04.013. Epub 2011 May 18.
5
A nutritionally-enhanced oil from transgenic Camelina sativa effectively replaces fish oil as a source of eicosapentaenoic acid for fish.一种来自转基因荠蓝的营养强化油可有效替代鱼油,作为鱼类二十碳五烯酸的来源。
Sci Rep. 2015 Jan 29;5:8104. doi: 10.1038/srep08104.
6
n-3 Oil sources for use in aquaculture--alternatives to the unsustainable harvest of wild fish.水产养殖中使用的n-3油源——野生鱼类不可持续捕捞的替代物
Nutr Res Rev. 2008 Dec;21(2):85-96. doi: 10.1017/S0954422408102414.
7
Metabolic engineering of the omega-3 long chain polyunsaturated fatty acid biosynthetic pathway into transgenic plants.将ω-3 长链多不饱和脂肪酸生物合成途径的代谢工程导入转基因植物。
J Exp Bot. 2012 Apr;63(7):2397-410. doi: 10.1093/jxb/err454. Epub 2012 Jan 30.
8
Towards sustainable sources for omega-3 fatty acids production.迈向可持续的ω-3 脂肪酸生产来源。
Curr Opin Biotechnol. 2014 Apr;26:14-8. doi: 10.1016/j.copbio.2013.08.003. Epub 2013 Sep 3.
9
An alternative to fish oils: Metabolic engineering of oil-seed crops to produce omega-3 long chain polyunsaturated fatty acids.替代鱼油:通过代谢工程改造油料作物生产ω-3 长链多不饱和脂肪酸。
Prog Lipid Res. 2010 Apr;49(2):108-19. doi: 10.1016/j.plipres.2009.10.001. Epub 2009 Oct 24.
10
Replacement of dietary fish oil for Atlantic salmon parr (Salmo salar L.) with a stearidonic acid containing oil has no effect on omega-3 long-chain polyunsaturated fatty acid concentrations.用含硬脂酸的油替代大西洋鲑鱼幼鱼(Salmo salar L.)日粮中的鱼油,对ω-3长链多不饱和脂肪酸浓度没有影响。
Comp Biochem Physiol B Biochem Mol Biol. 2007 Feb;146(2):197-206. doi: 10.1016/j.cbpb.2006.10.099. Epub 2006 Oct 21.

引用本文的文献

1
Sn1,3 Regiospecificity of DHA (22:6ω-3) of Plant Origin (DHA-Canola) Facilitates Its Preferential Tissue Incorporation in Rats Compared to sn2 DHA in Algal Oil at Low Dietary Inclusion Levels.植物源(低芥酸菜籽来源)DHA(二十二碳六烯酸,22:6ω-3)的Sn1,3区域特异性使其在低膳食添加水平下,相比于藻油中的Sn2 DHA,能更优先地整合到大鼠组织中。
Nutrients. 2025 Apr 9;17(8):1306. doi: 10.3390/nu17081306.
2
Fatty Acid Composition and Contents of Fish of Genus from Natural Ecosystems and Aquaculture.鱼类属的脂肪酸组成和含量:来自自然生态系统和水产养殖。
Biomolecules. 2022 Jan 16;12(1):144. doi: 10.3390/biom12010144.
3
Microalgae n-3 PUFAs Production and Use in Food and Feed Industries.

本文引用的文献

1
Stepwise engineering to produce high yields of very long-chain polyunsaturated fatty acids in plants.逐步工程化以在植物中高产超长链多不饱和脂肪酸。
Nat Biotechnol. 2005 Aug;23(8):1013-7. doi: 10.1038/nbt1107. Epub 2005 Jun 12.
2
Environmental and dietary influences on highly unsaturated fatty acid biosynthesis and expression of fatty acyl desaturase and elongase genes in liver of Atlantic salmon (Salmo salar).环境和饮食对大西洋鲑(Salmo salar)肝脏中高度不饱和脂肪酸生物合成以及脂肪酸去饱和酶和延长酶基因表达的影响。
Biochim Biophys Acta. 2005 May 1;1734(1):13-24. doi: 10.1016/j.bbalip.2005.01.006. Epub 2005 Mar 5.
3
微藻n-3多不饱和脂肪酸在食品和饲料工业中的生产与应用。
Mar Drugs. 2021 Feb 18;19(2):113. doi: 10.3390/md19020113.
4
Long-chain Omega-3 Polyunsaturated Fatty Acids in Natural Ecosystems and the Human Diet: Assumptions and Challenges.长链ω-3 多不饱和脂肪酸在自然生态系统和人类饮食中的作用:假设与挑战。
Biomolecules. 2019 Sep 12;9(9):485. doi: 10.3390/biom9090485.
5
Fatty Acid Composition and Contents of Seven Commercial Fish Species of Genus Coregonus from Russian Subarctic Water Bodies.俄罗斯亚北极水体中七种商业白鲑属鱼类的脂肪酸组成和含量
Lipids. 2017 Dec;52(12):1033-1044. doi: 10.1007/s11745-017-4304-8. Epub 2017 Sep 30.
6
Transgenic expression of delta-6 and delta-15 fatty acid desaturases enhances omega-3 polyunsaturated fatty acid accumulation in Synechocystis sp. PCC6803.转 基因表达 δ-6 和 δ-15 脂肪酸去饱和酶增强集胞藻 PCC6803 中 ω-3 多不饱和脂肪酸的积累。
Biotechnol Biofuels. 2014 Mar 1;7(1):32. doi: 10.1186/1754-6834-7-32.
7
Isolation and functional characterization of a delta 6-desaturase gene from the pike eel (Muraenesox cinereus).从梭鱼(Muraenesox cinereus)中分离并功能表征 delta 6-去饱和酶基因。
J Microbiol. 2013 Dec;51(6):807-13. doi: 10.1007/s12275-013-3144-3. Epub 2013 Oct 5.
8
Reconstitution of EPA and DHA biosynthesis in arabidopsis: iterative metabolic engineering for the synthesis of n-3 LC-PUFAs in transgenic plants.在拟南芥中重建 EPA 和 DHA 生物合成:用于转基因植物中 n-3 LC-PUFA 合成的迭代代谢工程。
Metab Eng. 2013 May;17:30-41. doi: 10.1016/j.ymben.2013.03.001. Epub 2013 Mar 14.
9
Enhancing the accumulation of omega-3 long chain polyunsaturated fatty acids in transgenic Arabidopsis thaliana via iterative metabolic engineering and genetic crossing.通过迭代代谢工程和遗传杂交提高转基因拟南芥中ω-3 长链多不饱和脂肪酸的积累。
Transgenic Res. 2012 Dec;21(6):1233-43. doi: 10.1007/s11248-012-9596-0. Epub 2012 Feb 19.
10
Echium acanthocarpum hairy root cultures, a suitable system for polyunsaturated fatty acid studies and production.海滨锦葵毛状根培养物,一种适合多不饱和脂肪酸研究和生产的体系。
BMC Biotechnol. 2011 Apr 27;11:42. doi: 10.1186/1472-6750-11-42.
Metabolic engineering of new fatty acids in plants.
植物中新脂肪酸的代谢工程。
Curr Opin Plant Biol. 2005 Apr;8(2):197-203. doi: 10.1016/j.pbi.2005.01.012.
4
Relief for fish stocks: oceanic fatty acids in transgenic oilseeds.鱼类种群的救星:转基因油籽中的海洋脂肪酸。
Trends Plant Sci. 2005 Mar;10(3):112-6. doi: 10.1016/j.tplants.2005.01.003.
5
Omega-3 (n-3) fatty acids in health and disease: Part 1--cardiovascular disease and cancer.欧米伽-3(n-3)脂肪酸与健康和疾病:第一部分——心血管疾病和癌症。
J Med Food. 2004 Winter;7(4):387-401. doi: 10.1089/jmf.2004.7.387.
6
Omega-3 fatty acids: molecular approaches to optimal biological outcomes.欧米伽-3脂肪酸:实现最佳生物学结果的分子途径
Curr Opin Lipidol. 2005 Feb;16(1):11-8. doi: 10.1097/00041433-200502000-00004.
7
Dietary intake of differently fed salmon; the influence on markers of human atherosclerosis.不同喂养方式的鲑鱼的饮食摄入;对人类动脉粥样硬化标志物的影响。
Eur J Clin Invest. 2005 Jan;35(1):52-9. doi: 10.1111/j.1365-2362.2005.01443.x.
8
Molecular cloning and functional characterization of fatty acyl desaturase and elongase cDNAs involved in the production of eicosapentaenoic and docosahexaenoic acids from alpha-linolenic acid in Atlantic salmon (Salmo salar).参与大西洋鲑(Salmo salar)从α-亚麻酸生成二十碳五烯酸和二十二碳六烯酸过程的脂肪酰去饱和酶和延长酶cDNA的分子克隆及功能表征
Mar Biotechnol (NY). 2004 Sep-Oct;6(5):463-74. doi: 10.1007/s10126-004-3002-8. Epub 2004 Nov 4.
9
Biosynthesis of very-long-chain polyunsaturated fatty acids in transgenic oilseeds: constraints on their accumulation.转基因油料种子中极长链多不饱和脂肪酸的生物合成:其积累的限制因素
Plant Cell. 2004 Oct;16(10):2734-48. doi: 10.1105/tpc.104.026070. Epub 2004 Sep 17.
10
Omega-3 fatty acids in colorectal cancer prevention.欧米伽-3脂肪酸在结直肠癌预防中的作用
Int J Cancer. 2004 Oct 20;112(1):1-7. doi: 10.1002/ijc.20320.