Bonneau J C
Laboratoire d'Immuno-allergologie, CHRU, Angers.
Allerg Immunol (Paris). 1992 May;24(5):157-9.
It was in 1923 that Coca and Cooke made a distinctive entity of a group of diseases of allergy, including asthma, and hay fever. They remarked that these affections were frequently associated and/or preceded by eczema localised to certain regions (flexor folds), sometimes generalised, perhaps appearing suddenly, from the third month in infants. In effect, the majority of constitutional eczema is in infants of 6 months, 75% of the cases are in one-year-old children. There is recovery in 5 years following the start of the affection in 90% of cases. Only 5% of cases persist to adulthood.
1923年,科卡(Coca)和库克(Cooke)将包括哮喘和花粉热在内的一组过敏性疾病确认为一种独特的病症。他们指出,这些病症常常相互关联,和/或在局限于某些部位(屈侧褶皱处)的湿疹之后出现,有时湿疹会泛发,可能突然出现,在婴儿三个月大时就会出现。实际上,大多数体质性湿疹发生在6个月大的婴儿身上,75%的病例发生在1岁儿童身上。90%的病例在发病后5年内痊愈。只有5%的病例会持续到成年。