Small cell carcinoma of the larynx treated with irinotecan and cisplatin.
作者信息
Sone Michihiko, Uchida Ikue, Tominaga Mitsuo, Sugiura Saiko, Nagasaka Testuro, Nakashima Tsutomu
机构信息
Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
出版信息
Auris Nasus Larynx. 2006 Jun;33(2):223-5. doi: 10.1016/j.anl.2005.09.002. Epub 2006 Jan 10.
We report a case of advanced small cell carcinoma in the larynx, which was treated with Irinotecan hydrochloride (CPT-11) chemotherapy. The patient was free of disease for 4 years after treatment. Several chemotherapeutic agents for small cell carcinoma have been proposed; however, median survival time has been miserable, especially in advanced cases. For the cure of the aggressive lethal behavior of this disease, chemotherapy with CPT-11 might be effective to improve median survival of patients with small cell carcinomas of the larynx.
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