在喂食胆固醇的大鼠中，热表异构茶儿茶素具有与绿茶儿茶素相同的降胆固醇活性。
Heat-epimerized tea catechins have the same cholesterol-lowering activity as green tea catechins in cholesterol-fed rats.
作者信息
Kobayashi Makoto, Unno Tomonori, Suzuki Yuko, Nozawa Ayumu, Sagesaka Yuko, Kakuda Takami, Ikeda Ikuo
机构信息
Central Research Institute, Ito En, Ltd., Shizuoka, Japan.
出版信息
Biosci Biotechnol Biochem. 2005 Dec;69(12):2455-8. doi: 10.1271/bbb.69.2455.
Tea catechins are known to be epimerized by heat treatment. The effect of heat-epimerized tea catechins on serum cholesterol concentration was compared with that of green tea catechins. Our observations strongly suggest that both tea catechins and heat-epimerized tea catechins lower serum cholesterol concentration by inhibiting cholesterol absorption in the intestine. There was no differential effect between the two catechin preparations.
已知茶儿茶素会因热处理而发生差向异构化。将热差向异构化茶儿茶素对血清胆固醇浓度的影响与绿茶儿茶素的影响进行了比较。我们的观察结果有力地表明，茶儿茶素和热差向异构化茶儿茶素均通过抑制肠道内胆固醇的吸收来降低血清胆固醇浓度。两种儿茶素制剂之间没有差异效应。
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