一种能够差异性支持大肠杆菌烟酰胺腺嘌呤二核苷酸营养缺陷型生长的代谢物的分离。
Isolation of a metabolite capable of differentially supporting the growth of nicotinamide adenine dinucleotide auxotrophs of Escherichia coli.
作者信息
Chen J L, Tritz G J
出版信息
J Bacteriol. 1975 Jan;121(1):212-8. doi: 10.1128/jb.121.1.212-218.1975.
Abstract
A compound, isolated from the culture fluid of a nadC auxotroph of Escherichia coli grown in a minimal medium, supports the growth of both a nadA and a nadB mutant. This metabolite exhibits an ultraviolet light absorption spectrum and a mass spectrum, different from quinolinic acid. This compound may be the precursor of quinolinic acid, an intermediate in the biosynthesis of nicotinamide adenosine dinucleotide.
摘要
从在基本培养基中生长的大肠杆菌nadC营养缺陷型的培养液中分离出的一种化合物，能支持nadA和nadB突变体的生长。这种代谢物呈现出不同于喹啉酸的紫外光吸收光谱和质谱。该化合物可能是喹啉酸的前体，而喹啉酸是烟酰胺腺嘌呤二核苷酸生物合成中的一种中间体。
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本文引用的文献
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Cross-feeding of Escherichia coli mutants defective in the biosynthesis of nicotinamide adenine dinucleotide.烟酰胺腺嘌呤二核苷酸生物合成缺陷的大肠杆菌突变体的交叉喂养
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