Rigamonti A, Usai S, Ciusani E, Bussone G
National Neurological Institute C. Besta, Via Celoria 11, I-20133 Milan, Italy.
Neurol Sci. 2005 Dec;26(5):351-4. doi: 10.1007/s10072-005-0506-6.
Cytomegalovirus (CMV)-associated transverse myelitis is rare in immunocompetent patients. We report a 73-year-old man with no evidence of immune compromise, who developed acute transverse myelitis. Cerebrospinal fluid pleocytosis indicated central nervous system inflammation, and spinal MRI showed weak signal hypointensity in T1, hyperintensity in T2 and DP between C7 and T2, but no contrast enhancement. High CSF anti- CMV IgG index with normal CSF IgG index indicated intact blood-brain barrier, and supported the diagnosis of CMV-induced myelitis in an immunocompetent patient.
巨细胞病毒(CMV)相关的横贯性脊髓炎在免疫功能正常的患者中较为罕见。我们报告一名73岁男性,无免疫功能受损证据,却发生了急性横贯性脊髓炎。脑脊液细胞增多提示中枢神经系统炎症,脊髓磁共振成像显示C7至T2节段T1加权像呈弱信号低强度、T2加权像及扩散加权像呈高强度,但无强化表现。脑脊液抗CMV IgG指数升高而脑脊液IgG指数正常,表明血脑屏障完整,支持免疫功能正常患者发生CMV诱导性脊髓炎的诊断。