Auger Sandrine, Krin Evelyne, Aymerich Stéphane, Gohar Michel
Microbiologie et Génétique Moléculaire, INRA (UMR1238), CNRS (UMR2585), INAPG, F-78850 Thiverval-Grignon, France.
Appl Environ Microbiol. 2006 Jan;72(1):937-41. doi: 10.1128/AEM.72.1.937-941.2006.
Cell-free supernatants from growing Bacillus cereus strain ATCC 10987 induced luminescence in a Photorhabdus luminescens DeltaluxS mutant, indicating the production of functional autoinducer 2 (AI-2). The exogenous addition of in vitro synthesized AI-2 had an inhibitory effect on biofilm formation by B. cereus and promoted release of the cells from a preformed biofilm.
生长中的蜡样芽孢杆菌ATCC 10987菌株的无细胞上清液可诱导发光杆菌属发光菌DeltaluxS突变体发光,表明其产生了功能性自诱导物2(AI-2)。体外合成的AI-2的外源添加对蜡样芽孢杆菌的生物膜形成具有抑制作用,并促进细胞从预先形成的生物膜中释放。