Khaustova N D, Totskiĭ V M, Strel'tsova N A
Genetika. 1992 May;28(5):73-80.
Properties and allelic ADH (alcohol dehydrogenase) control in Drosophila melanogaster were studied upon flies' cultivation under conditions of hypotherm of different intensity and duration. Lines homozygotic for F allele (vg) and S allele (cn) of the Adh gene as well as genetically enriched experimental cn' and vg' populations containing a small number of AdhF/AdhS heterozygotes at the initial stage were used. It was found out that physiological adaptation of the species to momentary influence of elevated temperature is accompanied by modification of physical properties of ADH-F according to ADH-S. Constant influence (during the life span of 25 generations) of elevated temperature on the population changes its genetic structure, due to selective advantages of the S allele of Adh under these conditions.
在不同强度和持续时间的低温条件下培养果蝇时，研究了黑腹果蝇中乙醇脱氢酶（ADH）的特性和等位基因控制。使用了对Adh基因的F等位基因（vg）和S等位基因（cn）纯合的品系，以及在初始阶段含有少量AdhF/AdhS杂合子的遗传富集实验cn'和vg'群体。结果发现，该物种对高温瞬间影响的生理适应伴随着ADH-F的物理性质根据ADH-S发生改变。在这些条件下，由于Adh的S等位基因具有选择优势，高温对群体的持续影响（在25代的寿命期间）改变了其遗传结构。
