Kawakami Eiichi, Masaoka Yosuke, Hirano Taichi, Hori Tatsuya, Tsutsui Toshihiko
Department of Reproduction, Nippon Veterinary and Animal Science University, Tokyo, Japan.
J Vet Med Sci. 2005 Dec;67(12):1249-52. doi: 10.1292/jvms.67.1249.
Three male Beagles with low plasma luteinizing hormone and testosterone levels and spermatogenic dysfunction (SD-dogs) were given 3 weekly subcutaneous injections of a gonadotropin-releasing hormone analogue (Buserelin; GnRH-AB). The plasma T level of all of the SD-dogs increased and peaked at 4-6 weeks after the first injection. The total number of sperm and the sperm motility of the three SD-dogs increased 5-7 weeks after the first injection. Therefore, the authors concluded that 3 weekly injections of GnRH-AB transiently improves semen quality in some cases of canine spermatogenic dysfunction.
对三只血浆促黄体生成素和睾酮水平较低且存在生精功能障碍的雄性比格犬（SD犬），每周皮下注射一次促性腺激素释放激素类似物（布舍瑞林；GnRH-AB），共注射3次。所有SD犬的血浆睾酮水平均升高，并在首次注射后4-6周达到峰值。三只SD犬的精子总数和精子活力在首次注射后5-7周增加。因此，作者得出结论，每周注射3次GnRH-AB在某些犬类生精功能障碍病例中可短暂改善精液质量。
