Larbcharoensub Noppadol, Chobpradit Napawan, Kijvikai Kittinut, Chalermsanyakorn Panas
Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Urol Int. 2006;76(1):94-6. doi: 10.1159/000089745.
A case of primary renal inflammatory myofibroblastic tumor of the left kidney in a 51-year-old man clinically presenting bleeding from the gums with thrombocytopenia and left flank mass is reported. Pathological examination of the left renal tumor characterizes macroscopically by a cortical mass and histologically by spindle cells admixed with variable amounts of extracellular collagen, lymphocytes and plasma cells. Immunohistological stainings are positive vimentin and focal positive smooth muscle actin. Clinical and pathological features with a brief review of the relevant literature are discussed. This is the first reported description in the literature of primary renal inflammatory myofibroblastic tumor associated with thrombocytopenia.
报告了一例51岁男性左肾原发性炎性肌纤维母细胞瘤病例,临床表现为牙龈出血伴血小板减少及左腰部肿块。左肾肿瘤的病理检查显示,大体上为皮质肿块,组织学上为梭形细胞,伴有不同数量的细胞外胶原、淋巴细胞和浆细胞。免疫组织化学染色显示波形蛋白阳性,平滑肌肌动蛋白局灶性阳性。讨论了临床和病理特征,并简要回顾了相关文献。这是文献中首次报道的与血小板减少相关的原发性肾炎性肌纤维母细胞瘤病例。