苏格兰运动神经元病登记册：苏格兰成人起病运动神经元病的前瞻性研究。1989年新发病例的方法学、人口统计学和临床特征。
The Scottish Motor Neuron Disease Register: a prospective study of adult onset motor neuron disease in Scotland. Methodology, demography and clinical features of incident cases in 1989.
出版信息
J Neurol Neurosurg Psychiatry. 1992 Jul;55(7):536-41. doi: 10.1136/jnnp.55.7.536.
Abstract
The Scottish Motor Neuron Disease Register (SMNDR) is a prospective, collaborative, population based study of motor neuron disease (MND) in Scotland. The register started in January 1989 with the aim of studying the clinical and epidemiological features of MND by prospectively identifying incident patients. It is based on a system of registration by recruitment from multiple sources, followed by the collection of complete clinical data and follow up, mainly through general practitioners. In this report the register's methodology and the demography and incidence data for the first year of study are presented. One hundred and fourteen newly diagnosed patients were identified in 1989 giving a crude incidence for Scotland of 2.24/100,000/year. Standardised incidence ratios showed a non-significant trend towards lower rates in north eastern regions and island areas.
摘要
苏格兰运动神经元病登记册（SMNDR）是一项针对苏格兰运动神经元病（MND）的前瞻性、合作性、基于人群的研究。该登记册始于1989年1月，旨在通过前瞻性识别新发病例来研究MND的临床和流行病学特征。它基于一个从多个来源招募进行登记的系统，随后收集完整的临床数据并进行随访，主要通过全科医生进行。在本报告中，介绍了登记册的方法以及研究第一年的人口统计学和发病率数据。1989年共识别出114例新诊断患者，苏格兰的粗发病率为每年2.24/10万。标准化发病率显示，东北地区和岛屿地区的发病率有降低的趋势，但不显著。
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