Vakirlis E, Kastanis A, Lazaridou E, Loannides D, Chrysomallis F
Department of Dermatology, Aristotle University of Thessaloniki, Greece.
Int J Clin Pharmacol Res. 2005;25(4):165-8.
We report a case of guttate psoriasis in a 28-year-old woman who had been suffering from scalp psoriasis from the age of 14. After an upper respiratory infection she presented with the typical exanthema of guttate psoriasis. Despite initial treatment with antibiotics and emollients, the rash continued to spread. Two months after the flare of psoriasis we decided to treat the patient with calcipotriol and betamethasone dipropionate ointment applied once daily, using an intermittent treatment modality. The lesions disappeared and despite two small recurrences on the legs we managed to maintain clearance after a 2-year follow-up. Although the application of calcipotriol and betamethasone dipropionate ointment was cumbersome, due to the extent of the eruption, the result was highly effective and safe without any lesional/perilesional adverse reaction during application and with normal blood examinations.
我们报告一例点滴状银屑病病例,患者为一名28岁女性,自14岁起就患有头皮银屑病。上呼吸道感染后,她出现了点滴状银屑病的典型皮疹。尽管最初使用抗生素和润肤剂进行治疗,但皮疹仍继续扩散。银屑病发作两个月后,我们决定采用间歇治疗方式,每天使用一次卡泊三醇倍他米松二丙酸酯软膏对患者进行治疗。皮损消失,尽管腿部有两次小的复发,但经过2年随访,我们成功维持了病情缓解。尽管由于皮疹范围较大,涂抹卡泊三醇倍他米松二丙酸酯软膏操作繁琐,但结果非常有效且安全,涂抹期间未出现任何皮损/皮损周围不良反应,血液检查结果也正常。