Soy Mehmet, Oktun Müşerref Tatman, Tunçbilek Nermin, Ermantaş Nilay, Okten Omür, Altinay Gündeniz, Turgut Burhan
Department of Rheumatology, Trakya University Faculty of Medicine, Edirne, 22100 Turkey.
Rheumatol Int. 2006 Mar;26(5):461-4. doi: 10.1007/s00296-005-0014-2. Epub 2006 Jan 10.
Antiphospholipid syndrome is an autoimmune disease that is characterised by tendency to thrombosis, obstetrical and hematological complications. Corticosteroids may be useful for therapy of some features of this syndrome, such as thrombocytopenia. Nocardia is an important opportunistic infectious agent in immunocompromised hosts, i.e. in patients taking corticosteroids. It is important to be aware of these rare complications, which are correlated with the prognosis. In this paper, we report a patient with primary anti-phospholipid syndrome treated by corticosteroid, who developed disseminated nocardiosis.
抗磷脂综合征是一种自身免疫性疾病，其特征为有血栓形成倾向、产科及血液学并发症。皮质类固醇可能有助于治疗该综合征的某些特征，如血小板减少症。诺卡菌是免疫功能低下宿主（即服用皮质类固醇的患者）中的一种重要的机会性感染病原体。认识到这些与预后相关的罕见并发症很重要。在本文中，我们报告了一名接受皮质类固醇治疗的原发性抗磷脂综合征患者，该患者发生了播散性诺卡菌病。
