Amerkhanova A M, Lavrova A E, Dmitrieva G V, Pyrikova I A, Zubkova E S, Zhilenkova O G, Kuralenko A A
Vestn Ross Akad Med Nauk. 2005(12):30-2.
The article is dedicated to a clinical trial of Bifidumbacterin Multi-1, a biologically active food supplement (BAFS) for children aged 0 to 3 years. The study showed that application of BAFS in children with intestinal dysbiosis helped to cope with the symptoms of alimentary disturbances, promoted improvement of body mass index, increase of hemoglobin end erythrocyte level, suppression of zymotic and putrefactive dyspepsia, decrease of inflammation of the intestinal mucosa, elimination of bibidobacterial deficit, and reduction of conditionally pathogenic microflora. Bifidumbacterin Multi-1 was well tolerated and highly effective according to clinical and laboratory data. This preparation may be recommended as a component of complex therapy in children aged 0 to 3 years old.
本文致力于对双歧杆菌四联活菌片（适用于0至3岁儿童的一种生物活性食品补充剂）进行临床试验。研究表明，在患有肠道菌群失调的儿童中应用该生物活性食品补充剂有助于应对消化紊乱症状，促进体重指数改善、血红蛋白和红细胞水平升高、抑制发酵性和腐败性消化不良、减轻肠黏膜炎症、消除双歧杆菌缺乏以及减少条件致病性微生物群。根据临床和实验室数据，双歧杆菌四联活菌片耐受性良好且疗效显著。该制剂可推荐作为0至3岁儿童综合治疗的一个组成部分。
