Aleshkin V A, Lapin B A, Afanas'ev S S, Pospelova V V, Dzhikidze E K, Afanas'ev M S
Vestn Ross Akad Med Nauk. 2006(2):11-5.
The parameters of colon microbiocenosis were evaluated in healthy animals belonging to 6 species of marmosets; its disorders typical of patients with different forms of acute intestinal infections were revealed. Bifidoflora of young monkeys was characterized. The study demonstrated multiple similarities of the microflora of monkeys and humans, including small children. A preclinical study of dry bifidin, a probiotic, revealed its advantages over the commercial bifidumbacterin. 90 monkeys were used for preclinical evaluation of complex immunoglobulin preparation (CIP) and a combination of CIP with interferon (kipferon in suppositories). The study demonstrated sanifying and microflora-normalizing effects, increase of anti-microbial antibodies and serum interferon after both parenteral and rectal administration. The protective activity of a new variant of the probiotic Acilact in exposure to ionizing radiation and anticancer chemotherapy under experimental conditions
对属于6种狨猴的健康动物的结肠微生物群落参数进行了评估；揭示了不同形式急性肠道感染患者典型的肠道紊乱情况。对幼猴的双歧杆菌群落进行了特征描述。该研究证明了猴子与人类（包括幼儿）微生物群的多重相似性。对益生菌干双歧菌素的临床前研究揭示了其相对于市售双歧杆菌素的优势。90只猴子用于复合免疫球蛋白制剂（CIP）以及CIP与干扰素（栓剂中的基普费龙）组合的临床前评估。该研究证明了经肠胃外和直肠给药后具有净化和使微生物群正常化的作用，抗菌抗体和血清干扰素增加。在实验条件下，新型益生菌阿西拉克在暴露于电离辐射和抗癌化疗时的保护活性
