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[The neuroprotector effect of a new taurine derivative on a model of compression spinal cord trauma in rats].

作者信息

Sapronov N S, Bul'on V V, Kuznetsova N N, Selina E N

出版信息

Eksp Klin Farmakol. 2005 Nov-Dec;68(6):45-8.

PMID:16405035
Abstract

The neuroprotector effect of a new taurine derivative, 2-(1-phenylethyl)-aminoethanesulfonyl-2-propylamide hydrochloride, has been studied in rats with model compression spinal cord trauma. The drug favored restoration of the motor function of posterior extremities in rats with the model spinal cord trauma and significantly decreased the lethality in test animals. The taurine derivative normalized the energy metabolism, lipid peroxidation and antioxidant system in animals with spinal cord trauma. The neuroprotector effect of the new taurine derivative significantly exceeds the action of cerebrolysine.

摘要

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