Department of Community and Family Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China.
Clin Exp Dermatol. 2010 Jan;35(1):16-21. doi: 10.1111/j.1365-2230.2009.03340.x. Epub 2009 May 26.
Data are lacking on the prevalence of acne, its effects on quality of life (QOL) and the treatment usage among Chinese patients in late adolescence.
To derive data about the prevalence and predictive factors of acne, the disability caused by acne and choice of treatment used by Chinese late adolescents in Hong Kong.
This was a cross-sectional study of a random sample of 389 entrants in a university in Hong Kong, using the Global Acne Grading System (GAGS) to measure the clinical severity of acne and the Cardiff Acne Disability Index (CADI) to measure QOL.
The response rate was 99.3%. The prevalence of acne was of 81.5% (95% CI 77.6-85.4%) and coexisted with a high frequency of acne disability at a rate of 81.8% (95% CI 78.1-85.6%). Assessment of the clinical severity of acne did not correlate strongly with the effect on QOL (gamma(s) = 0.445, P < 0.001). Over the previous 6 months, 30.3% of subjects had used topical treatments, 3.9% had taken systemic conventional western drugs and 3.2% of the subjects had used traditional Chinese medicine. Multivariate logistic regression was used to explore the predictive factors for acne disability. Female gender (P = 0.002), higher GAGS score (P < 0.001), higher perceived stress (P = 0.01) and willingness to pay Hong Kong$15,000 (970 pounds) for a hypothetical permanent cure (P = 0.03) were positive predictors.
Acne is prevalent in Hong Kong and has considerable psychological effects. The association between clinical severity and impaired QOL is not strong.
目前缺乏中国青少年痤疮的流行率、对生活质量的影响以及治疗方法的使用情况的数据。
了解香港青少年痤疮的流行率和预测因素、痤疮引起的残疾情况以及治疗方法的选择。
这是一项对香港一所大学的随机样本 389 名参与者进行的横断面研究,使用全球痤疮分级系统(GAGS)来衡量痤疮的临床严重程度,使用加的夫痤疮残疾指数(CADI)来衡量生活质量。
应答率为 99.3%。痤疮的患病率为 81.5%(95%CI 77.6-85.4%),同时存在高频率的痤疮残疾率为 81.8%(95%CI 78.1-85.6%)。痤疮的临床严重程度评估与生活质量的影响相关性不强(γ(s) = 0.445,P < 0.001)。在过去的 6 个月中,30.3%的受试者使用了局部治疗,3.9%的受试者使用了传统的西药物治疗,3.2%的受试者使用了中药。多元逻辑回归用于探索痤疮残疾的预测因素。女性(P = 0.002)、GAGS 评分较高(P < 0.001)、感知压力较高(P = 0.01)和愿意支付 15000 港元(970 英镑)治疗假设的永久性治愈(P = 0.03)是积极的预测因素。
痤疮在香港很普遍,对心理健康有较大影响。临床严重程度与生活质量受损之间的关联并不强。