Xu Duan, Chen Albert P, Cunningham Charles, Osorio Joseph A, Nelson Sarah J, Vigneron Daniel B
Joint UCSF/UCB Graduate Group in Bioengineering, University of California, San Francisco and Berkeley, CA 94143, USA.
Magn Reson Imaging. 2006 Jan;24(1):69-74. doi: 10.1016/j.mri.2005.10.019. Epub 2005 Dec 19.
The goal of this study was to develop and evaluate high-resolution magnetic resonance spectroscopic imaging (MRSI) utilizing the gains in signal-to-noise ratio (SNR) provided by combining higher magnetic field with high-sensitivity phased-array (PA) coils. We investigated the maximum improvement in spatial resolution as small as 0.09 cm(3) for brain MRSI while maintaining adequate SNR and acquisition time. The use of low peak power, dual-band spectral-spatial pulses was also investigated for application to 3 T MRSI of the brain using the body coil for radiofrequency excitation and PA coils for signal reception.
本研究的目的是利用更高磁场与高灵敏度相控阵（PA）线圈相结合所提供的信噪比（SNR）增益，开发并评估高分辨率磁共振波谱成像（MRSI）。我们研究了脑MRSI在保持足够的SNR和采集时间的同时，空间分辨率最小可达0.09 cm³的最大提升。还研究了使用低峰值功率的双频谱空间脉冲，将其应用于使用体线圈进行射频激发和PA线圈进行信号接收的3T脑MRSI。
