Nizami S S, Khan M A, Naim Z, Islam M N, Azeem S W
Department of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Pak J Pharm Sci. 1993 Jan;6(1):97-9.
Carissa carandas belongs to family apocynaceae which consists of 300 genera and 1000 species. It is a large shrub with simple thorn and commonly cultivated throughout Pakistan for hedges and is called "Kakronda". The different parts of this plant have been used for various systems of medicine (Kirtikar et al., 1993). Cardiotonic activity was found in root of this plant (Rastogi et al., 1966; Rastogi et al., 1967; Vohra et al., 1963). This plant has been mentioned in the old chemical literature as purgative, stomachic, antihelmintics and antidote for snake-bite (Kirtikar., 1933). The physical characteristics of oil from the fruits of Carissa carandas were determined by using standard methods. In addition to this a study of sugars and amino acids from the fruits of this plant was also undertaken by the present authors (Naim et al., 1986). Our studies in the chemical investigation on this plant had led to the isolation of two new triterpene carissol Ia (Naim et al., 1985) and carissic acid lb (Naim et al., 1988).
刺黄果属夹竹桃科，该科有300属1000种。它是一种有单刺的大灌木，在巴基斯坦各地普遍种植用作树篱，被称为“Kakronda”。这种植物的不同部位已被用于各种医学体系（基尔蒂卡尔等人，1993年）。在这种植物的根中发现了强心活性（拉斯托吉等人，1966年；拉斯托吉等人，1967年；沃拉等人，1963年）。在旧的化学文献中，这种植物被提及有泻下、健胃、驱虫和蛇咬解毒作用（基尔蒂卡尔，1933年）。采用标准方法测定了刺黄果果实油的物理特性。除此之外，作者还对这种植物果实中的糖和氨基酸进行了研究（奈姆等人，1986年）。我们对这种植物的化学研究已导致分离出两种新的三萜类化合物——卡里索醇Ia（奈姆等人，1985年）和卡里酸Ib（奈姆等人，1988年）。
