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[活动性甲状腺眼病患者的泪膜特征]

[Tear film profile in patients with active thyroid orbithopathy].

作者信息

Nowak Mariusz, Marek Bogdan, Kos-Kudła Beata, Kajdaniuk Dariusz, Siemińska Lucyna

机构信息

Z Zakładu Patofizjologii Katedry Patofizjologii i Endokrynologii Slaskiej Akademii Medycznej w Katowicach.

出版信息

Klin Oczna. 2005;107(7-9):479-82.

PMID:16417002
Abstract

Dry eye symptoms and tear film profile were examined in 21 patients with Graves' disease complicated by active thyroid orbitopathy (OT). Dry eye symptoms and clinical tests: break-up time (BUT), Schirmer I, fluorescein and lissamine green staining in OT patients, were comparable with control group. Dry eye symptoms were present in 85% of OT patients compared with 30% in control group. BUT (5.84 +/- 3,31sec.) and Schirmer test (11.11 +/- 9,14mm) were significantly lower when compared with control group (11.4 +/- 3,75sec and 20.5 +/- 9,65mm). Lissamin green staining intensity score (3.61 +/- 1,74) as well as positive fluorescein staining in OT patients, were significantly higher when compared with control.

摘要

对21例合并活动性甲状腺眼病(OT)的格雷夫斯病患者的干眼症状和泪膜情况进行了检查。干眼症状及临床检查:OT患者的泪膜破裂时间(BUT)、泪液分泌试验I、荧光素和丽丝胺绿染色,与对照组相当。85%的OT患者有干眼症状,而对照组为30%。与对照组(11.4±3.75秒和20.5±9.65毫米)相比,OT患者的BUT(5.84±3.31秒)和泪液分泌试验(11.11±9.14毫米)明显更低。与对照组相比,OT患者的丽丝胺绿染色强度评分(3.61±1.74)以及荧光素染色阳性率明显更高。

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