Langmead L, Rampton D S
Department of Gastroenterology, University College London Hospitals, NHS Foundation Trust, London, UK.
Aliment Pharmacol Ther. 2006 Feb 1;23(3):341-9. doi: 10.1111/j.1365-2036.2006.02761.x.
Complementary and alternative medicine includes a wide range of practices and therapies outside the realms of conventional western medicine. Despite a lack of scientific data in the form of controlled trials for either efficacy or safety of complementary and alternative medicine, use by patients with inflammatory bowel disease, particularly of herbal therapies, is widespread and increasing. There is limited controlled evidence indicating efficacy of traditional Chinese medicines, aloe vera gel, wheat grass juice, Boswellia serrata and bovine colostrum enemas in ulcerative colitis. Encouraging results have also been reported in small studies of acupuncture for Crohn's disease and ulcerative colitis. Contrary to popular belief, natural therapies are not necessarily safe: fatal hepatic and irreversible renal failure have occurred with some preparations and interactions with conventional drugs are potentially dangerous. There is a need for further controlled clinical trials of the potential efficacy of complementary and alternative approaches in inflammatory bowel disease, together with enhanced legislation to maximize their quality and safety.
补充和替代医学包括传统西医领域之外的广泛实践和疗法。尽管缺乏关于补充和替代医学疗效或安全性的对照试验形式的科学数据，但炎症性肠病患者对其的使用，尤其是草药疗法的使用，却很普遍且呈上升趋势。仅有有限的对照证据表明中药、芦荟凝胶、小麦草汁、锯叶棕和牛初乳灌肠剂对溃疡性结肠炎有效。关于针灸治疗克罗恩病和溃疡性结肠炎的小型研究也报告了令人鼓舞的结果。与普遍看法相反，自然疗法不一定安全：一些制剂已导致致命性肝损伤和不可逆肾衰竭，且与传统药物的相互作用可能很危险。有必要对补充和替代方法在炎症性肠病中的潜在疗效进行进一步的对照临床试验，并加强立法以最大限度地提高其质量和安全性。
