Department of Biomedical Sciences, Arthur A. Dugoni School of Dentistry, University of the Pacific, 155 Fifth Street, San Francisco, CA 94103, USA.
Department of Biology, College of Science, Sultan Qaboos University, Muscat 123, Oman.
Molecules. 2022 Jun 29;27(13):4174. doi: 10.3390/molecules27134174.
trees, found throughout the Middle East and parts of Africa and Asia, are the source of frankincense oil. Since antiquity, frankincense has been traded as a precious commodity, but it has also been used for the treatment of chronic disease, inflammation, oral health, and microbial infection. More recently, the bioactive components of trees have been identified and characterized for their effects on cancer, microbial infection (especially infection by oral pathogens), and inflammation. Most studies have focused on cell lines, but more recent research has also investigated effects in animal models of disease. As natural products are considered to be safer than synthetic drugs, there is growing interest in further developing the use of substances such as frankincense oil for therapeutic treatment.
乳香树,遍布中东、部分非洲和亚洲地区,是乳香精油的来源。自古以来,乳香作为一种珍贵的商品进行交易,但它也被用于治疗慢性疾病、炎症、口腔健康和微生物感染。最近,乳香树的生物活性成分已被确定和表征,以研究其对癌症、微生物感染(特别是口腔病原体感染)和炎症的作用。大多数研究都集中在细胞系上,但最近的研究也调查了疾病动物模型中的作用。由于天然产物被认为比合成药物更安全,因此人们越来越有兴趣进一步开发乳香精油等物质用于治疗。