Bemt L, Vries M P, Knapen L, Jansen M, Goossens M, Muris J W M, Schayck C P
Department of General Practice, Research Institute Caphri, Maastricht University, The Netherlands.
Clin Exp Allergy. 2006 Feb;36(2):233-7. doi: 10.1111/j.1365-2222.2006.02427.x.
Exposure to a high level of house dust mite allergens (HDMAs) is considered as a risk factor for HDM sensitization and development of asthma in genetically disposed people. Mattresses are one of the most important sources of HDMA in people's living environment.
The aim of this study was to evaluate the association between mattress characteristics and HDMA concentrations on mattresses.
Dust samples of mattress surfaces were taken to evaluate the level of Der p 1 allergen. All participants filled in a questionnaire about the type of mattress, the type of covering (upper layer) of the mattress, dwelling characteristics and cleaning habits. Humidity and temperature of the bedroom were measured at the time of dust sampling.
One hundred and sixty-eight questionnaires were filled in. Synthetic upper layer of the mattress was associated with a higher level of Der p 1 compared with cotton upper layer (2.6 vs. 0.8 microg/g Der p 1). Moreover, higher relative humidity (RH) was associated with significant higher concentrations and density of Der p 1.
Two factors were associated with lower levels of Der p 1 found on mattresses, namely: a cotton upper layer of the mattress compared with a layer of synthetic material and lower RH at the time of sampling. As far as we know, the association between type of upper layer and concentration of Der p 1 has not been described before and could lead to the formulation of practical advices in order to reduce HDMA concentrations on mattresses.
接触高水平的屋尘螨过敏原（HDMAs）被认为是遗传易感性人群中HDM致敏和哮喘发病的危险因素。床垫是人们生活环境中HDMA的最重要来源之一。
本研究旨在评估床垫特性与床垫上HDMA浓度之间的关联。
采集床垫表面的灰尘样本以评估Der p 1过敏原水平。所有参与者填写了一份关于床垫类型、床垫覆盖物（上层）类型、居住特征和清洁习惯的问卷。在采集灰尘样本时测量卧室的湿度和温度。
共填写了168份问卷。与棉质上层相比，床垫的合成上层与更高水平的Der p 1相关（2.6 vs. 0.8微克/克Der p 1）。此外，较高的相对湿度（RH）与Der p 1的显著更高浓度和密度相关。
有两个因素与床垫上较低水平的Der p 1相关，即：与合成材料层相比，床垫的棉质上层以及采样时较低的RH。据我们所知，上层类型与Der p 1浓度之间的关联以前尚未被描述，这可能会导致制定实用建议以降低床垫上的HDMA浓度。
