Lowe Michael R, Davis William, Lucks Dara, Annunziato Rachel, Butryn Meghan
Drexel University, USA.
Physiol Behav. 2006 Mar 30;87(3):487-92. doi: 10.1016/j.physbeh.2005.11.011. Epub 2006 Jan 26.
Bulimic individuals typically lose a substantial amount of weight in the process of developing their disorder. Such weight suppression (WS) may be behaviorally and metabolically problematic. The present study tested the hypothesis that WS would predict weight gain during the inpatient hospitalization of 146 bulimia nervosa-spectrum inpatients. WS represented the difference (M=12.0 kg) between highest weight ever and current body weight. Controlling for length of stay and current dieting (EAT-D scores), high levels of WS predicted greater weight gain. Furthermore, WS and admission BMI independently predicted weight gain when entered together in a regression analysis. Weight gain was also related to clinical improvement. These findings suggest that weight suppression, independently of current dieting status, may produce psychobiological pressures toward weight gain and could complicate the treatment of bulimia nervosa.
患有暴食症的个体在其疾病发展过程中通常会体重大幅下降。这种体重抑制（WS）在行为和代谢方面可能存在问题。本研究检验了这样一个假设：体重抑制能够预测146名神经性贪食症谱系住院患者在住院期间的体重增加情况。体重抑制代表了曾经的最高体重与当前体重之间的差异（M = 12.0千克）。在控制住院时长和当前节食情况（EAT - D得分）后，高水平的体重抑制预示着更大幅度的体重增加。此外，在回归分析中，当体重抑制和入院时的身体质量指数（BMI）一起纳入时，它们能独立预测体重增加情况。体重增加也与临床改善相关。这些发现表明，体重抑制独立于当前的节食状态，可能会产生促使体重增加的心理生物学压力，并且可能使神经性贪食症的治疗复杂化。
