McKay A M
Food and Agricultural Microbiology Research Division, Department of Agriculture for Northern Ireland, Belfast, UK.
J Appl Bacteriol. 1992 Jun;72(6):475-8. doi: 10.1111/j.1365-2672.1992.tb01861.x.
The toxic glycosides vicine and convicine which are present in fababeans have been implicated in favism, an anaemic disease of humans. Vicine and convicine concentrations are reduced by growth of Lactobacillus plantarum on fababean suspensions. The glycosides are eliminated from the fababean substrate by the growth of the filamentous fungus Fusarium graminearum. Incubation of fababean suspension with concentrated culture filtrate of Aspergillus oryzae, induced for extracellular beta-glucosidase production, results in complete degradation of the glycosides. This study suggests a potential use of micro-organisms or microbial enzymes for detoxification of fababeans.
蚕豆中存在的毒性糖苷蚕豆嘧啶和伴蚕豆嘧啶与人类的一种贫血病——蚕豆病有关。植物乳杆菌在蚕豆悬浮液上生长可降低蚕豆嘧啶和伴蚕豆嘧啶的浓度。丝状真菌禾谷镰刀菌的生长可从蚕豆底物中消除这些糖苷。用诱导产生细胞外β-葡萄糖苷酶的米曲霉浓缩培养滤液孵育蚕豆悬浮液，可导致糖苷完全降解。本研究表明微生物或微生物酶在蚕豆解毒方面具有潜在用途。
