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荚膜红细菌四吡咯生物合成途径中的氧调节步骤。

Oxygen-regulated steps in the Rhodobacter capsulatus tetrapyrrole biosynthetic pathway.

作者信息

Biel A J

机构信息

Department of Microbiology, Louisiana State University, Baton Rouge 70803.

出版信息

J Bacteriol. 1992 Aug;174(16):5272-4. doi: 10.1128/jb.174.16.5272-5274.1992.

Abstract

The effect of exogenous aminolevulinate and porphobilinogen on protoporphyrin accumulation in Rhodobacter capsulatus was measured. Oxygen inhibited protoporphyrin accumulation in strain AJB456, a bchH mutant, even in the presence of exogenous aminolevulinate, suggesting that some step in the formation of protoporphyrin from aminolevulinate is regulated by oxygen. In contrast, in the presence of exogenous porphobilinogen, oxygen did not inhibit protoporphyrin accumulation. The results presented in this study indicate that oxygen regulates the formation of porphobilinogen from aminolevulinate.

摘要

测定了外源氨基乙酰丙酸和胆色素原对荚膜红细菌中原卟啉积累的影响。氧气抑制了bchH突变体AJB456菌株中原卟啉的积累,即使存在外源氨基乙酰丙酸,这表明从氨基乙酰丙酸形成原卟啉的某些步骤受氧气调节。相反,在存在外源胆色素原的情况下,氧气并不抑制原卟啉的积累。本研究给出的结果表明,氧气调节从氨基乙酰丙酸形成胆色素原的过程。

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