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精神分裂症中存在“错误性”学习缺陷?

An "errorful" learning deficit in schizophrenia?

作者信息

Pope Jay W, Kern Robert S

机构信息

Fuller Graduate School of Psychology, Pasadena, CA, USA.

出版信息

J Clin Exp Neuropsychol. 2006 Jan;28(1):101-10. doi: 10.1080/13803390490918138.

Abstract

Disturbances in learning are prominent in schizophrenia. The present study examined the effect of committing mistakes (errors) on learning in schizophrenia. Subjects included schizophrenia and schizoaffective disorder patients (n = 36) and healthy adults (n = 22) who were administered a word-stem completion task under "errorfree" (no guessing) and "errorful" (guessing) conditions. The data were analyzed using a 2 (group) x 2 (order) x 2 (condition) repeated-measures ANOVA and by comparing standard residualized scores between patients and controls. The results from the ANOVA revealed a significant group x condition interaction with patients showing greater impairment relative to controls on the errorful versus errorfree condition. Similarly, contrasts of standard residualized scores revealed patients' scores on the errorful condition to be deviant from that of healthy adults. The findings implicate problems in the ability to self-correct and suggest that rehabilitation efforts incorporating errorless learning methods may benefit persons with schizophrenia.

摘要

学习障碍在精神分裂症中很突出。本研究考察了犯错(失误)对精神分裂症患者学习的影响。研究对象包括精神分裂症和分裂情感性障碍患者(n = 36)以及健康成年人(n = 22),他们在“无错误”(不猜测)和“有错误”(猜测)条件下接受词干补全任务。数据采用2(组)×2(顺序)×2(条件)重复测量方差分析,并通过比较患者与对照组的标准残差分数进行分析。方差分析结果显示,组×条件存在显著交互作用,与对照组相比,患者在有错误条件下比无错误条件下表现出更大的损伤。同样,标准残差分数对比显示,患者在有错误条件下的分数与健康成年人不同。研究结果表明自我纠正能力存在问题,并提示采用无错误学习方法的康复措施可能对精神分裂症患者有益。

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