Timmerman M F, van der Weijden G A
Department of Periodontology, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.
Int J Dent Hyg. 2006 Feb;4(1):2-7. doi: 10.1111/j.1601-5037.2006.00168.x.
This review presents a selected overview of the literature concerning risk factors for periodontitis. That in some individuals gingivitis develops into periodontitis is still a matter of extensive research. Cross-sectional studies of clinical and microbiological factors can be meaningful. Longitudinal studies of the natural history allow analysis of potential factors and conditions that may have an impact on the disease process. At present, several possible risk factors for the initiation and progression of periodontitis have been identified: age, gender, plaque, calculus, existing attachment loss. A consistent finding appears to be genetic predisposition for the development of the disease. In terms of microbiology, several micro-organisms have been identified. The results of the Java Project on natural development of Periodontal Disease clearly pinpoint Actinobacillus actinimycetemcomitans as being associated with the onset of disease. The presence of subgingival calculus was found to be associated with onset and dental plaque with progression of disease. Consistent with literature males are more susceptible to disease. The presence of pockets > or = 5 mm appear to be a useful tool, since it was found to be a prognostic factor for disease progression.
本综述对有关牙周炎危险因素的文献进行了精选概述。在一些个体中,牙龈炎会发展成牙周炎,这仍是广泛研究的课题。临床和微生物学因素的横断面研究可能具有意义。对自然病程的纵向研究能够分析可能对疾病进程产生影响的潜在因素和状况。目前,已确定了几种可能导致牙周炎发生和进展的危险因素:年龄、性别、牙菌斑、牙结石、现有附着丧失。一个一致的发现似乎是该疾病发展存在遗传易感性。在微生物学方面,已鉴定出几种微生物。牙周疾病自然发展的爪哇项目结果明确指出伴放线放线杆菌与疾病发作有关。发现龈下牙结石的存在与疾病发作有关,而牙菌斑与疾病进展有关。与文献一致的是,男性更易患该病。存在≥5毫米的牙周袋似乎是一个有用的指标,因为它被发现是疾病进展的一个预后因素。