Aalizadeh Yasmina, Khamisi Nima, Asghari Parastoo, Safari Amirhossein, Mottaghi Mahtab, Taherkhani Mohamad Hosein, Alemi Anahita, Ghaderi Masoume, Rahmanian Mohammad
Department of Pediatric Dentistry, School of Dentistry, Islamic Azad University (khorasgan Branch), IAU (Khorasgan Branch), University Blvd, Jey St, Arqavanieh, Isfahan, 81551-39998, Iran.
School of Dentistry, Islamic Azad University (Khorasgan Branch), IAU (Khorasgan Branch), University Blvd, Jey St, Arqavanieh, Isfahan, 81551-39998, Iran.
Heliyon. 2024 Aug 5;10(15):e35633. doi: 10.1016/j.heliyon.2024.e35633. eCollection 2024 Aug 15.
Periodontitis is a severe oral health condition that affects the soft tissue and bone supporting the teeth. The Mediterranean diet has been proposed as a potential contributor to reducing the risk of periodontitis. This systematic review and meta-analysis aims to explore the association between adherence to the Mediterranean diet and periodontitis. A comprehensive literature search from 1992 to January 2024 was conducted across multiple databases, including PubMed, Scopus, Web of Science, and Google Scholar. The included studies were clinical trials, randomized controlled trials, and observational studies that evaluated the impact of the Mediterranean diet on periodontitis. Data extraction and quality assessment of the included studies were performed using standardized protocols. A meta-analysis was conducted to combine effect sizes from multiple studies. This review included seven studies, comprising one cohort study, five cross-sectional studies, and one randomized controlled trial. While some studies reported a potential link between Mediterranean diet adherence and periodontitis, the overall analysis did not demonstrate a significant association. The meta-analysis revealed an Odds Ratio (95 % Confidence Interval) of 0.77 (0.58, 1.03) for the association between adherence to the Mediterranean diet and periodontitis = . This systematic review and meta-analysis found no statistically significant association between periodontitis and Mediterranean diet adherence. Future research should prioritize the implementation of rigorous clinical studies with longer follow-up periods to better understand the causal association between the Mediterranean diet and periodontitis. Observational studies with larger sample sizes are needed to establish more conclusive evidence regarding the impact of dietary patterns on periodontal health.
牙周炎是一种严重的口腔健康状况，会影响支持牙齿的软组织和骨骼。地中海饮食被认为可能有助于降低患牙周炎的风险。本系统评价和荟萃分析旨在探讨坚持地中海饮食与牙周炎之间的关联。我们在多个数据库中进行了全面的文献检索，时间跨度从1992年至2024年1月，这些数据库包括PubMed、Scopus、科学网和谷歌学术。纳入的研究为评估地中海饮食对牙周炎影响的临床试验、随机对照试验和观察性研究。使用标准化方案对纳入研究进行数据提取和质量评估。进行荟萃分析以合并多项研究的效应量。本综述纳入了七项研究，包括一项队列研究、五项横断面研究和一项随机对照试验。虽然一些研究报告了坚持地中海饮食与牙周炎之间可能存在联系，但总体分析并未显示出显著关联。荟萃分析显示，坚持地中海饮食与牙周炎之间关联的优势比（95%置信区间）为0.77（0.58，1.03），P = 。本系统评价和荟萃分析发现，牙周炎与坚持地中海饮食之间无统计学上的显著关联。未来的研究应优先开展随访期更长的严谨临床研究，以更好地了解地中海饮食与牙周炎之间的因果关系。需要开展样本量更大的观察性研究，以确立关于饮食模式对牙周健康影响的更确凿证据。
