Van der Velden U, Abbas F, Armand S, Loos B G, Timmerman M F, Van der Weijden G A, Van Winkelhoff A J, Winkel E G
Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands.
J Clin Periodontol. 2006 Aug;33(8):540-8. doi: 10.1111/j.1600-051X.2006.00953.x.
To identify risk factors, risk predictors and risk determinants for onset and progression of periodontitis.
For this longitudinal, prospective study all subjects in the age range 15-25 years living in a village of approximately 2000 inhabitants at a tea estate on Western Java, Indonesia, were selected. Baseline examination was carried out in 1987 and follow-up examinations in 1994 and 2002. In 2002, 128 subjects could be retrieved from the original group of 255. Baseline examination included evaluation of plaque, bleeding on probing, calculus, pocket depth, attachment loss and presence of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, spirochetes and motile microorganisms.
The mean attachment loss increased from 0.33 mm in 1987 to 0.72 mm in 1994 and 1.97 mm in 2002. Analysis identified the amount of subgingival calculus and subgingival presence of A. actinomycetemcomitans as risk factors, and age as a risk determinant, for the onset of disease. Regarding disease progression, the number of sites with a probing depth > or = 5 mm and the number of sites with recession were identified as risk predictors and male gender as a risk determinant.
Screening of these parameters early in life could be helpful in the prevention of onset and progression of periodontal diseases.
确定牙周炎发病和进展的风险因素、风险预测指标及风险决定因素。
在印度尼西亚西爪哇一个约有2000名居民的茶叶种植园村庄,选取年龄在15 - 25岁的所有受试者进行这项纵向、前瞻性研究。1987年进行基线检查,1994年和2002年进行随访检查。2002年,从最初的255名受试者中找回了128名。基线检查包括对菌斑、探诊出血、牙石、牙周袋深度、附着丧失以及伴放线放线杆菌、牙龈卟啉单胞菌、中间普氏菌、螺旋体和运动微生物的存在情况进行评估。
平均附着丧失从1987年的0.33mm增加到1994年的0.72mm以及2002年的1.97mm。分析确定龈下牙石量和龈下伴放线放线杆菌的存在为疾病发病的风险因素,年龄为风险决定因素。关于疾病进展,探诊深度≥5mm的部位数量和牙龈退缩部位数量被确定为风险预测指标,男性性别为风险决定因素。
在生命早期对这些参数进行筛查可能有助于预防牙周疾病的发病和进展。